Evidence map›Paper›PMID 23886048›Full record

ArticleAIDS patient care and STDs2013

The association of clinical follow-up intervals in HIV-infected persons with viral suppression on subsequent viral suppression.

April Buscher, Michael Mugavero, Andrew O Westfall, Jeanne Keruly, Richard Moore, Mari-Lynn Drainoni, Meg Sullivan, Tracey E Wilson, Allan Rodriguez, Lisa Metsch and 4 more

Abstract read
In one paragraph

Article in AIDS patient care and STDs, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Enhanced personal contact with HIV patients improves retention in primary care: a randomized trial in 6 US HIV clinics.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014
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  11. Measuring the HIV Care Continuum Using Public Health Surveillance Data in the United States.Journal of acquired immune deficiency syndromes (1999) · 2015
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  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

April BuscherBaylor College of Medicine, Thomas Street Health Center, Houston, TX, USA.
Michael Mugavero
Andrew O Westfall
Jeanne Keruly
Richard Moore
Mari-Lynn Drainoni
Meg Sullivan
Tracey E Wilson
Allan Rodriguez
Lisa Metsch
Lytt Gardner
Gary Marks
Faye Malitz
Thomas P Giordano

Funding

University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALLAN E RODRIGUEZ · 2007 to 2026
$33.8M
TRAINING PROGRAM FOR CLINICAL RESEARCH ON AIDST32AI007456 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI SHEARER, WILLIAM THOMAS · 1992 to 2012
$2.8M
NIAID NIH HHS P30 AI073961NIAID NIH HHS T32AI07456PHS HHS 200-2007-23684PHS HHS 200-2007-23685PHS HHS 200-2007-23687PHS HHS 200-2007-23689PHS HHS 200-2007-23690PHS HHS 200-2007-23692
6 · The paper itself

Abstract

The recommendation for the frequency for routine clinical monitoring of persons with well-controlled HIV infection is based on evidence that relies on observed rather than intended follow-up intervals. We sought to determine if the scheduled follow-up interval is associated with subsequent virologic failure. Participants in this 6-clinic retrospective cohort study had an index clinic visit in 2008 and HIV viral load (VL) ≤400 c/mL. Univariate and multivariate tests evaluated if scheduling the next follow-up appointment at 3, 4, or 6 months predicted VL >400 c/mL at 12 months (VF). Among 2171 participants, 66%, 26%, and 8% were scheduled next follow-up visits at 3, 4, and 6 months, respectively. With missing 12-month VL considered VF, 25%, 25%, and 24% of persons scheduled at 3, 4, and 6 months had VF, respectively (p=0.95). Excluding persons with missing 12-month VL, 7.1%, 5.7%, and 4.5% had VF, respectively (p=0.35). Multivariable models yielded nonsignificant odds of VF by scheduled follow-up interval both when missing 12-month VL were considered VF and when persons with missing 12-month VL were excluded. We conclude that clinicians are able to make safe decisions extending follow-up intervals in persons with viral suppression, at least in the short-term.

Indexed as

Appointments and SchedulesAdultAnti-HIV AgentsFemaleFollow-Up StudiesHIV InfectionsHumansMaleMultivariate AnalysisOffice VisitsRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeViral LoadYoung AdultAnti-HIV Agents

Identifiers

PMID23886048
PMCPMC3739946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.