ReviewFrontiers in cellular and infection microbiology2013
Anaplasma phagocytophilum--a widespread multi-host pathogen with highly adaptive strategies.
Review in Frontiers in cellular and infection microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 294 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
294 citing papers in PubMed, 9 syntheses or guidelines pooled it, 595 citations in OpenAlex.
- Global prevalence of Anaplasma species infection in domestic small ruminants: a systematic review and meta-analysis.Tropical animal health and production · 2026Pooled it
- Prevalence and associated factors of Anaplasma, Rickettsia, and Coxiella-related bacteria in ticks in China: A systematic review and meta-analysis.Experimental & applied acarology · 2026Pooled it
- A Systematic Review on the Occurrence ofPathogens (Basel, Switzerland) · 2025Pooled it
- Anaplasma Phagocytophilum, a Zoonotic Vector-Borne Bacterial Species in Rodents and Its Associated Tick Vector: Systematic Review.Veterinary medicine and science · 2025Pooled it
- Global Prevalence of Anaplasma phagocytophilum in Cattle: A One Health Perspective, Meta-Analysis and Future Predictions (up to 2035).Veterinary medicine and science · 2025Pooled it
- Global trends in tick research: a comprehensive visualization and bibliometric study (2015-2024).Frontiers in cellular and infection microbiology · 2025Pooled it
- Global prevalence of Borrelia burgdorferi and Anaplasma phagocytophilum coinfection in wild and domesticated animals: A systematic review and meta-analysis.Journal of global health · 2024Pooled it
- Tick-Borne Diseases in Sub-Saharan Africa: A Systematic Review of Pathogens, Research Focus, and Implications for Public Health.Pathogens (Basel, Switzerland) · 2024Pooled it
- Global prevalence and species diversity of tick-borne pathogens in buffaloes worldwide: a systematic review and meta-analysis.Parasites & vectors · 2023Pooled it
- First Molecular Report of Haemaphysalis shimoga and Haemaphysalis bispinosa Infesting Captive Sambar Deer (Rusa unicolor) in Malaysia, with Detection of Anaplasma phagocytophilum and Theileria Co-infection.Acta parasitologica · 2026Article
- Global Trends in Vaccine Research onMicroorganisms · 2026Review
- The Roles of Contrasting Host Types on the Environmental Abundance ofEcology and evolution · 2026Article
- Serological Survey on the Occurrence of Bacterial Tick-Borne Pathogens in Cattle and Dogs from Bolivian Chaco.Veterinary sciences · 2026Article
- Molecular Survey of Selected Tick-Borne Pathogens and Genetic Diversity ofMicroorganisms · 2026Article
- Immuno-Informatics Design of Multi-Epitope Vaccine Candidate AgainstHealth science reports · 2026Article
- Beyond Dominant Symbionts: Low-Abundance Taxa Govern Microbial Network Topology in Sympatric Ticks.Microbial ecology · 2026Article
- Early-life exposure to vector-borne pathogens in moose calves from Finland: molecular and phylogenetic evidence.BMC veterinary research · 2026Article
- Tick Microbiome and Its Role in Emerging Zoonotic Diseases and Transmissibility.Microorganisms · 2026Review
- Serological and Molecular Detection of Zoonotic Pathogens in European Bison (Pathogens (Basel, Switzerland) · 2026Article
- Sympatric Occurrence of Five Exophilic Tick Species in the Levice Region (Southwestern Slovakia) and Their Infection with Tick-Borne Pathogens.Pathogens (Basel, Switzerland) · 2026Article
234 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The bacterium Anaplasma phagocytophilum has for decades been known to cause the disease tick-borne fever (TBF) in domestic ruminants in Ixodes ricinus-infested areas in northern Europe. In recent years, the bacterium has been found associated with Ixodes-tick species more or less worldwide on the northern hemisphere. A. phagocytophilum has a broad host range and may cause severe disease in several mammalian species, including humans. However, the clinical symptoms vary from subclinical to fatal conditions, and considerable underreporting of clinical incidents is suspected in both human and veterinary medicine. Several variants of A. phagocytophilum have been genetically characterized. Identification and stratification into phylogenetic subfamilies has been based on cell culturing, experimental infections, PCR, and sequencing techniques. However, few genome sequences have been completed so far, thus observations on biological, ecological, and pathological differences between genotypes of the bacterium, have yet to be elucidated by molecular and experimental infection studies. The natural transmission cycles of various A. phagocytophilum variants, the involvement of their respective hosts and vectors involved, in particular the zoonotic potential, have to be unraveled. A. phagocytophilum is able to persist between seasons of tick activity in several mammalian species and movement of hosts and infected ticks on migrating animals or birds may spread the bacterium. In the present review, we focus on the ecology and epidemiology of A. phagocytophilum, especially the role of wildlife in contribution to the spread and sustainability of the infection in domestic livestock and humans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.