Evidence map›Paper›PMID 23885159›Full record

ArticleWorld journal of gastroenterology2013

Hepatic adenoma mimicking a metastatic lesion on computed tomography-positron emission tomography scan.

Darryl Lim, Ser Yee Lee, Kiat Hon Lim, Chung Yip Chan

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. PET-avid hepatocellular adenomas: incidental findings associated with HNF1-α mutated lesions.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2016
    Article
  8. False-positiveThe Indian journal of radiology & imaging
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Darryl LimDepartment of General Surgery, Singapore General Hospital, Singapore 169608, Singapore.
Ser Yee Lee
Kiat Hon Lim
Chung Yip Chan
Singapore General Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Positron emission tomography (PET) using ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) is an imaging modality which reflects cellular glucose metabolism. Most malignant cells accumulate and trap ¹⁸F-FDG, allowing the visualisation of increased uptake. It is hence widely used to differentiate malignant from benign lesions. "False positive" findings of hepatic lesions have been described in certain instances such as hepatic abscesses, but are rare in cases involving hepatocellular adenomas. To our knowledge, there have been only 7 reports in the English literature documenting PET-avid hepatocellular adenomas; 6 of the 7 reports were published in the last 3 years with the first report by Patel et al. We report the case of a 44-year-old Chinese female patient with a history of cervical adenocarcinoma, referred for a hepatic lesion noted on a surveillance computed tomography (CT) scan. A subsequent CT-PET performed showed a hypermetabolic lesion (standardized uptake value 7.9) in segment IVb of the liver. After discussion at a multi-disciplinary hepato-pancreato-biliary conference, the consensus was that of a metastatic lesion from her previous cervical adenocarcinoma, and a resection of the hepatic lesion was performed. Histology revealed features consistent with a hepatocyte nuclear factor-1 α inactivated steatotic hepatocellular adenoma.

Indexed as

Positron-Emission TomographyTomography, X-Ray ComputedAdenomaAdultDiagnosis, DifferentialFalse Positive ReactionsFemaleFluorodeoxyglucose F18HumansHypoxia-Inducible Factor 1, alpha SubunitHysterectomyLiver NeoplasmsMultimodal ImagingRadiopharmaceuticalsUterine Cervical NeoplasmsFluorodeoxyglucose F18HIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitRadiopharmaceuticals18F-fluorodeoxyglucoseHepatic adenomaHepatocellular adenomaHepatocyte nuclear factor-1 αPositron emission tomography

Identifiers

PMID23885159
PMCPMC3718916
OpenAlexW1979406066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.