ArticleThe Journal of infectious diseases2013
Menstrual cycle and detectable human papillomavirus in reproductive-age women: a time series study.
Article in The Journal of infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of self-collected menstrual blood for high-risk human papillomavirus testing for cervical intraepithelial neoplasia and cervical cancer: a systematic review and meta-analysis.Frontiers in microbiology · 2026Pooled it
- Tracking the Impact of Excisional Cervical Treatment on the Cervix using Biospectroscopy.Scientific reports · 2016Trial
- Review
- CareHPV, Papanicolaou Positivity Status, and Their Association With Behavioral Risk Factors in Rural Women of Kamrup District, Assam, India.Cancer reports (Hoboken, N.J.) · 2024Article
- Article
- Endogenous oestradiol and progesterone as predictors of oncogenic human papillomavirus (HPV) persistence.BMC cancer · 2022Article
- Importance of Lifetime Sexual History on the Prevalence of Genital Human Papillomavirus (HPV) Among Unvaccinated Adults in the National Health and Nutrition Examination Surveys: Implications for Adult HPV Vaccination.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Association of asymptomatic bacterial vaginosis with persistence of female genital human papillomavirus infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Article
- Review
- Mechanistic mathematical models: An underused platform for HPV research.Papillomavirus research (Amsterdam, Netherlands) · 2017Review
- Intermittent nasal carriage with Staphylococcus aureus within a menstrual cycle: Results from a prospective cohort of healthy carriers.Medicine · 2016Article
- Tracking vaginal, anal and oral infection in a mouse papillomavirus infection model.The Journal of general virology · 2015Article
- Characterizing the temporal dynamics of human papillomavirus DNA detectability using short-interval sampling.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014Article
- Obesity and human papillomavirus infection in perimenopausal women.The Journal of infectious diseases · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundCurrent evidence on the relationship between human papillomavirus (HPV) DNA detection and menstrual cycle has been inconsistent.
methodsWe included 21 nonoral contraceptive pill (non-OCP) users who self-collected vaginal samples twice per week for 16 weeks. We explored whether variable detection of HPV DNA exhibited cyclic or other structured temporal patterns. We also evaluated relationships between serial HPV prevalence, sexual behavior, and suspected bacterial vaginosis (BV) as defined by Nugent Gram stain score ≥7.
resultsDuring follow-up, any-type HPV prevalence varied between 61.1% and 85.0%. Although not statistically significant, we observed a maximum autocorrelation in serial HPV prevalence lagging 14 days (correlation coefficient [ρ], -0.24). Any-type HPV detection had a periodic behavior, generally repeating every 28.0 days (bootstrapped interquartile range, 22.4-28.0) and peaking around the ovulation time (adjusted odds ratio, 1.96; 95% confidence interval [CI], 1.06-3.62) as compared to menstruation. We also showed that an increase in any-type HPV prevalence preceded the beginning of a menstrual cycle by 9-12 days. There was no evidence of relationships between HPV prevalence and sexual activity or Nugent score.
conclusionsSerially detected any-type HPV DNA showed a periodic behavior and was likely to peak in the periovulatory phase among non-OCP users.
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