ArticleReproductive sciences (Thousand Oaks, Calif.)2014
Differential gene expression profiling of mouse uterine luminal epithelium during periimplantation.
Article in Reproductive sciences (Thousand Oaks, Calif.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 41 citations in OpenAlex.
- Advances and challenges of endometrial organoids in modeling endometrial function: basic, clinical, and future perspectives.Frontiers in bioengineering and biotechnology · 2026Review
- Loss of Parkinson Disease Protein 7 (PARK7) upregulates ROS and cell migration and is associated with recurrent pregnancy loss.Molecular medicine (Cambridge, Mass.) · 2025Article
- Functions of RhoA in the female reproductive system.Reproductive and developmental medicine · 2025Review
- Article
- Exogenous estrogen partially rescues progesterone deficiency and autophagosome enlargement inReproductive and developmental medicine · 2024Article
- H3K27me3 timely dictates uterine epithelial transcriptome remodeling and thus transformation essential for normal embryo implantation.Cell death and differentiation · 2024Article
- Proteomic analysis reveals dynamic changes in cloacal fluid composition during the reproductive season in a sexually promiscuous passerine.Scientific reports · 2024Article
- Attenuated retinoic acid signaling is among the early responses in mouse uterus approaching embryo attachment.Reproductive and developmental medicine · 2024Article
- Visualization of preimplantation uterine fluid absorption in mice using Alexa Fluor™ 488 Hydrazide†.Biology of reproduction · 2023Article
- Differential Signals From TNFα-Treated and Untreated Embryos in Uterine Tissues and Splenic CD4Frontiers in veterinary science · 2021Article
- Functions of Lysosomes in Mammalian Female Reproductive System.Reproductive and developmental medicine · 2020Article
- Regulation of coenzyme A levels by degradation: the 'Ins and Outs'.Progress in lipid research · 2020Review
- Uterine Luminal Epithelium as the Transient Gateway for Embryo Implantation.Trends in endocrinology and metabolism: TEM · 2020Review
- Association of luteal cell degeneration and progesterone deficiency with lysosomal storage disorder mucolipidosis type IV in Mcoln1-/- mouse model†.Biology of reproduction · 2019Article
- Identification of Gene Expression Changes Associated With Uterine Receptivity in Mice.Frontiers in physiology · 2019Article
- Seipin deficiency leads to increased endoplasmic reticulum stress and apoptosis in mammary gland alveolar epithelial cells during lactation.Biology of reproduction · 2018Article
- Functional proteomic profiling reveals KLK13 and TMPRSS11D as active proteases in the lower female reproductive tract.F1000Research · 2018Article
- Seipin deficiency leads to defective parturition in mice.Biology of reproduction · 2017Article
- Deletion of RhoA in Progesterone Receptor-Expressing Cells Leads to Luteal Insufficiency and Infertility in Female Mice.Endocrinology · 2017Article
- Acidification of uterine epithelium during embryo implantation in mice.Biology of reproduction · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
Uterine luminal epithelium (LE) is critical for establishing uterine receptivity. Microarray analysis of gestation day 3.5 (D3.5, preimplantation) and D4.5 (postimplantation) LE from natural pregnant mice identified 382 upregulated and 245 downregulated genes in the D4.5 LE. Gene Ontology annotation grouped 186 upregulated and 103 downregulated genes into 22 and 15 enriched subcategories, respectively, in regulating DNA-dependent transcription, metabolism, cell morphology, ion transport, immune response, apoptosis, signal transduction, and so on. Signaling pathway analysis revealed 99 genes in 21 significantly changed signaling pathways, with 14 of these pathways involved in metabolism. In situ hybridization confirmed the temporal expression of 12 previously uncharacterized genes, including Atp6v0a4, Atp6v0d2, F3, Ggh, Tmprss11d, Tmprss13, Anpep, Fxyd4, Naip5, Npl, Nudt19, and Tpm1 in the periimplantation uterus. This study provides a comprehensive picture of the differentially expressed genes in the periimplantation LE to help understand the molecular mechanism of LE transformation upon establishment of uterine receptivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.