ArticleInternational urology and nephrology2013
Assessment of glomerular filtration rate in elderly patients with chronic kidney disease.
Article in International urology and nephrology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Article
- Estimating renal function in old people: an in-depth review.International urology and nephrology · 2017Review
- Evaluation of glomerular filtration rate by different equations in Chinese elderly with chronic kidney disease.International urology and nephrology · 2017Article
- An efficient approach for glomerular filtration rate assessment in older adults.British journal of clinical pharmacology · 2014Article
- Application of creatinine- and/or cystatin C-based glomerular filtration rate estimation equations in elderly Chinese.Clinical interventions in aging · 2014Article
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Authors and funding
7 authors.
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Abstract
purposeWe sought to evaluate various glomerular filtration rate (GFR) estimating equations in elderly patients with chronic kidney disease (CKD).
methodsA total of 332 Chinese elderly patients with CKD who had undergone technetium-99m diethylenetriaminepentaacetic acid ((99m)Tc-DTPA) renal dynamic imaging were enrolled. The MDRD equation, the re-expressed MDRD equation, the Chinese equation, the Ruijin equation, the previously Japanese equation, the new Japanese equation, the CKD-EPI equation, and the BIS1 equation were compared.
resultsThe median of difference between estimated GFR and standard GFR ranged from -9.78 to 1.79 ml/min/1.73 m(2). The interquartile range of difference ranged from 12.38 to 20.87 ml/min/1.73 m(2). Accuracy with a deviation <30 % ranged from 44.9 to 66.3 %. However, none of the equations had accuracy up to the 70 % level. Bland-Altman analysis demonstrated that the precision ranged from 50.5-87.6 ml/min/1.73 m(2). The slopes of regression line ranged from -0.26 to 0.55 and the intercepts ranged from -18.71 to 11.07. In both the overall performance and the performances in different stage of CKD, GFR estimated by the BIS1 equation performed better results.
conclusionNone of the GFR estimating equations are suitable for the specific Chinese population tested. At present, the BIS1 equation may be the optimal one for elderly Chinese CKD patients.
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