ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2013
Large deletions in the CBF gene cluster at the Fr-B2 locus are associated with reduced frost tolerance in wheat.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Optimizing wheat development to a range of winter climates.Journal of experimental botany · 2026Review
- From Shared Mechanisms to Precision Breeding: Engineering Cold and Drought Cross-Tolerance in Crops.International journal of molecular sciences · 2026Review
- Impact of Soil Drought on Yield and Leaf Sugar Content in Wheat: Genotypic and Phenotypic Relationships Compared Using a Doubled Haploid Population.International journal of molecular sciences · 2025Article
- How Structural Variations Influence Crop Improvement.International journal of molecular sciences · 2025Review
- Exogenous Spermidine Alleviated Low-Temperature Damage by Affecting Polyamine Metabolism and Antioxidant Levels in Apples.Plants (Basel, Switzerland) · 2024Article
- Current status for utilization of cold resistance genes and strategies in wheat breeding program.Frontiers in genetics · 2024Review
- TheCells · 2023Review
- Wheat genomic study for genetic improvement of traits in China.Science China. Life sciences · 2022Review
- Association mapping of autumn-seeded rye (Secale cereale L.) reveals genetic linkages between genes controlling winter hardiness and plant development.Scientific reports · 2022Article
- Phenology and related traits for wheat adaptation.Heredity · 2020Review
- Foliar Application of Polyamines Modulates Winter Oilseed Rape Responses to Increasing Cold.Plants (Basel, Switzerland) · 2020Article
- Transcriptomic response of durum wheat to cold stress at reproductive stage.Molecular biology reports · 2019Article
- Improving and Maintaining Winter Hardiness and Frost Tolerance in Bread Wheat by Genomic Selection.Frontiers in plant science · 2019Article
- Chromosome-scale comparative sequence analysis unravels molecular mechanisms of genome dynamics between two wheat cultivars.Genome biology · 2018Article
- Genomic Regions Associated with Tolerance to Freezing Stress and Snow Mold in Winter Wheat.G3 (Bethesda, Md.) · 2017Article
- Effect of the Winter Wheat Cheyenne 5A Substituted Chromosome on Dynamics of Abscisic Acid and Cytokinins in Freezing-Sensitive Chinese Spring Genetic Background.Frontiers in plant science · 2017Article
- Breeding approaches and genomics technologies to increase crop yield under low-temperature stress.Plant cell reports · 2017Review
- Copy number variation at the HvCBF4-HvCBF2 genomic segment is a major component of frost resistance in barley.Plant molecular biology · 2016Article
- Copy number variation of CBF-A14 at the Fr-A2 locus determines frost tolerance in winter durum wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2016Article
- Frost trends and their estimated impact on yield in the Australian wheatbelt.Journal of experimental botany · 2015Article
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8 authors.
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Abstract
Wheat plants which are exposed to periods of low temperatures (cold acclimation) exhibit increased survival rates when they are subsequently exposed to freezing temperatures. This process is associated with large-scale changes in the transcriptome which are modulated by a set of tandemly duplicated C-repeat Binding Factor (CBF) transcription factors located at the Frost Resistance-2 (Fr-2) locus. While Arabidopsis has three tandemly duplicated CBF genes, the CBF family in wheat has undergone an expansion and at least 15 CBF genes have been identified, 11 of which are present at the Fr-2 loci on homeologous group 5 chromosomes. We report here the discovery of three large deletions which eliminate 6, 9, and all 11 CBF genes from the Fr-B2 locus in tetraploid and hexaploid wheat. In wild emmer wheat, the Fr-B2 deletions were found only among the accessions from the southern sub-populations. Among cultivated wheats, the Fr-B2 deletions were more common among varieties with a spring growth habit than among those with a winter growth habit. Replicated freezing tolerance experiments showed that both the deletion of nine CBF genes in tetraploid wheat and the complete Fr-B2 deletion in hexaploid wheat were associated with significant reductions in survival after exposure to freezing temperatures. Our results suggest that selection for the wild-type Fr-B2 allele may be beneficial for breeders selecting for varieties with improved frost tolerance.
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