ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2014
Disease-specific perception of fracture risk and incident fracture rates: GLOW cohort study.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Incidence of fractures among patients with rheumatoid arthritis: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Pooled it
- Expressed information needs of patients with osteoporosis and/or fragility fractures: a systematic review.Archives of osteoporosis · 2018Pooled it
- Multiple sclerosis increases fracture risk: a meta-analysis.BioMed research international · 2015Pooled it
- Parkinson's disease and risk of fracture: a meta-analysis of prospective cohort studies.PloS one · 2014Pooled it
- Evaluation of a Multimodal, Direct-to-Patient Educational Intervention Targeting Barriers to Osteoporosis Care: A Randomized Clinical Trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018Trial
- Beyond Fracture Probability: Communicating the Full Consequences of Fracture and Contextualization.Current osteoporosis reports · 2026Review
- Fractures in Parkinson's Disease: Pathophysiology, Prevention, and Orthopedic Outcomes.Cureus · 2025Review
- Clinical and demographic factors determining patient fracture risk decision point (FRDP): The improving risk communication in osteoporosis (RICO) project.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Overlap between Osteosarcopenia and Frailty and their Association with Poor Health Conditions: The Bushehr Elderly Health Program.Annals of geriatric medicine and research · 2024Article
- Using machine learning to identify patients at high risk of developing low bone density or osteoporosis after gastrectomy: a 10-year multicenter retrospective analysis.Journal of cancer research and clinical oncology · 2023Article
- Investigating the relationship between self-perception of fracture risk and prior fracture: findings from the Hertfordshire Cohort Study.Aging clinical and experimental research · 2023Article
- Interrelations between clinical-psychological features and bone mineral density changes in post-menopausal women undergoing anti-osteoporotic treatment: a two-year follow-up.Frontiers in endocrinology · 2023Article
- The Association of Coronary Artery Calcium Score and Osteoporosis in Postmenopausal Women: A Cross-Sectional Study.Journal of bone metabolism · 2022Article
- Prevalence of Osteoporosis Assessed by DXA and/or CT in Severe Obese Patients.Journal of clinical medicine · 2022Article
- Osteoporosis in 2022: Care gaps to screening and personalised medicine.Best practice & research. Clinical rheumatology · 2022Review
- Fracture risk and impact of osteoporosis in patients with Parkinson's disease: a nationwide database study.Journal of bone and mineral metabolism · 2022Article
- Osteosarcopenia-The Role of Dual-Energy X-ray Absorptiometry (DXA) in Diagnostics.Journal of clinical medicine · 2022Review
- Improving uptake of Fracture Prevention drug treatments: a protocol for Development of a consultation intervention (iFraP-D).BMJ open · 2021Article
- Use of path modeling to inform a clinical decision support application to encourage osteoporosis medication use.Research in social & administrative pharmacy : RSAP · 2021Article
- Opportunistic diagnosis of osteoporosis, fragile bone strength and vertebral fractures from routine CT scans; a review of approved technology systems and pathways to implementation.Therapeutic advances in musculoskeletal disease · 2021Review
Corrections and comments
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Authors and funding
24 authors at 12 institutions in 9 countries.
Funding
Abstract
unlabelledAccurate patient risk perception of adverse health events promotes greater autonomy over, and motivation towards, health-related lifestyles.
introductionWe compared self-perceived fracture risk and 3-year incident fracture rates in postmenopausal women with a range of morbidities in the Global Longitudinal study of Osteoporosis in Women (GLOW).
methodsGLOW is an international cohort study involving 723 physician practices across ten countries (Europe, North America, Australasia); 60,393 women aged ≥55 years completed baseline questionnaires detailing medical history and self-perceived fracture risk. Annual follow-up determined self-reported incident fractures.
resultsIn total 2,945/43,832 (6.8%) sustained an incident fracture over 3 years. All morbidities were associated with increased fracture rates, particularly Parkinson's disease (hazard ratio [HR]; 95% confidence interval [CI], 3.89; 2.78-5.44), multiple sclerosis (2.70; 1.90-3.83), cerebrovascular events (2.02; 1.67-2.46), and rheumatoid arthritis (2.15; 1.53-3.04) (all p < 0.001). Most individuals perceived their fracture risk as similar to (46%) or lower than (36%) women of the same age. While increased self-perceived fracture risk was strongly associated with incident fracture rates, only 29% experiencing a fracture perceived their risk as increased. Under-appreciation of fracture risk occurred for all morbidities, including neurological disease, where women with low self-perceived fracture risk had a fracture HR 2.39 (CI 1.74-3.29) compared with women without morbidities.
conclusionsPostmenopausal women with morbidities tend to under-appreciate their risk, including in the context of neurological diseases, where fracture rates were highest in this cohort. This has important implications for health education, particularly among women with Parkinson's disease, multiple sclerosis, or cerebrovascular disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.