Evidence map›Paper›PMID 23884295›Full record

ReviewCurrent opinion in pulmonary medicine2013

Nonsteroidal therapy of sarcoidosis.

Peter Korsten, Mehdi Mirsaeidi, Nadera J Sweiss

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in pulmonary medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 46 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. The clinical management of hepatic sarcoidosis: A systematic review.JGH open : an open access journal of gastroenterology and hepatology · 2024
    Review
  5. Pulmonary granulomatosis of genetic origin.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. [Musculoskeletal manifestations of sarcoidosis].Zeitschrift fur Rheumatologie · 2017
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Management of extrapulmonary sarcoidosis: challenges and solutions.Therapeutics and clinical risk management · 2016
    Review
  16. [Interstitial nephritis in rheumatic diseases].Zeitschrift fur Rheumatologie · 2015
    Review
  17. Article
  18. Adalimumab-induced lupus serositis.BMJ case reports · 2015
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Peter KorstenDepartment of Nephrology and Rheumatology, University Medicine Göttingen, Göttingen, Germany.
Mehdi Mirsaeidi
Nadera J Sweiss
GTx (United States) · USUniversitätsmedizin Göttingen · DEUniversity of Illinois Chicago · US

Funding

Pulmonary and Critical Care Post-Doctoral Research Training ProgramT32HL082547 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FINN, PATRICIA W · 2007 to 2017
$2.7M
NHLBI NIH HHS T32 HL082547
6 · The paper itself

Abstract

purpose of reviewNone of the medications used in clinical practice to treat sarcoidosis have been approved by the regulatory authorities. Understanding how to use disease-modifying antisarcoid drugs, however, is essential for physicians treating patients with sarcoidosis. This review summarizes the recent studies of medications used for sarcoidosis with a focus on nonsteroidal therapies. Studies from 2006 to 2013 were considered for review to update clinicians on the most relevant literature published over the last few years. RECENT

findingsSeveral recently published pieces of evidence have helped expand our ability to more appropriately sequence second-line and third-line therapies for sarcoidosis. For instance, methotrexate and azathioprine may be useful and well tolerated medications as second-line treatment. Mycophenolate mofetil might have a role in neurosarcoidosis. TNF-α blockers and other biologics seem to be well tolerated medications for the most severely affected patients. SUMMARY: Corticosteroids remain the first-line therapy for sarcoidosis as many patients never require treatment or only necessitate a short treatment duration. Second-line and third-line therapies described in this article should be used in patients with progressive or refractory disease or when life-threatening complications are evident at the time of presentation.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalAzathioprineBiological ProductsHumansImmunosuppressive AgentsMethotrexateMycophenolic AcidSarcoidosis, PulmonaryTreatment OutcomeTumor Necrosis Factor-alphaAnti-Inflammatory Agents, Non-SteroidalAzathioprineBiological ProductsImmunosuppressive AgentsMethotrexateMycophenolic AcidTumor Necrosis Factor-alpha

Identifiers

PMID23884295
PMCPMC4134017
OpenAlexW2061180681

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.