ArticleEuropean journal of nuclear medicine and molecular imaging2013
Gated SPECT evaluation of left ventricular function using a CZT camera and a fast low-dose clinical protocol: comparison to cardiac magnetic resonance imaging.
Article in European journal of nuclear medicine and molecular imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Relationship between myocardial perfusion abnormalities and contractile impairment in anginal patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Trial
- A novel dynamic cardiac phantom for comparing blood pool and myocardial perfusion tracers: initial evaluation with CZT-ERNA and PET-MPI.EJNMMI physics · 2026Article
- Cardiovascular magnetic resonance for the diagnosis and management of heart failure with preserved ejection fraction.Heart failure reviews · 2022Review
- Capabilities of Modern Semiconductor Gamma Cameras in Radionuclide Diagnosis of Coronary Artery Disease.Diagnostics (Basel, Switzerland) · 2021Review
- Head-to-head comparison of diagnostic accuracy of stress-only myocardial perfusion imaging with conventional and cadmium-zinc telluride single-photon emission computed tomography in women with suspected coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Prognostic Value of Diastolic Dysfunction Derived From D-SPECT in Coronary Artery Disease Patients With Normal Ejection Fraction.Frontiers in cardiovascular medicine · 2021Article
- Assessment of four different cardiac softwares for evaluation of LVEF with CZT-SPECT vs CMR in 48 patients with recent STEMI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Children of a lesser god: From radiocardiogram to CZT GSPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Left ventricular eccentricity index measured with SPECT myocardial perfusion imaging: An additional parameter of adverse cardiac remodeling.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Real-time gated-SPECT myocardial perfusion imaging with CZT detectors: A promising tool for monitoring left ventricular function.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Prospective diagnostic performance of semiconductor SPECT myocardial perfusion imaging: wall thickening analysis reduces the need for an additional prone acquisition.European journal of nuclear medicine and molecular imaging · 2019Article
- EANM procedural guidelines for myocardial perfusion scintigraphy using cardiac-centered gamma cameras.European journal of hybrid imaging · 2019Article
- Evaluation of left ventricular mass on cadmium-zinc-telluride imaging: Validation against cardiac magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Comparison of CZT SPECT and conventional SPECT for assessment of contractile function, mechanical synchrony and myocardial scar in patients with heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Routine evaluation of left ventricular function using CZT-SPECT, with low injected activities and limited recording times.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- American perspective: Comparing the AHA/ACC and ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Myocardial ischemia in the absence of obstructive coronary lesion: The role of post-stress diastolic dysfunction in detecting early coronary atherosclerosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Detection of ischemia with early myocardial perfusion imaging: You see more if you watch before.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Accuracy of myocardial perfusion imaging in detecting multivessel coronary artery disease: A cardiac CZT study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Performance of cardiac cadmium-zinc-telluride gamma camera imaging in coronary artery disease: a review from the cardiovascular committee of the European Association of Nuclear Medicine (EANM).European journal of nuclear medicine and molecular imaging · 2016Review
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8 authors.
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Abstract
purposeCZT technology allows ultrafast low-dose myocardial scintigraphy but its accuracy in assessing left ventricular function is still to be defined.
methodsThe study group comprised 55 patients (23 women, mean age 63 ± 9 years) referred for myocardial perfusion scintigraphy. The patients were studied at rest using a CZT camera (Discovery NM530c; GE Healthcare) and a low-dose (99m)Tc-tetrofosmin clinical protocol (mean dose 264 ± 38 MBq). Gated SPECT imaging was performed as a 6-min list-mode acquisition, 15 min after radiotracer injection. Images were reformatted (8-frame to 16-frame) using Lister software on a Xeleris workstation (GE Healthcare) and then reconstructed with a dedicated iterative algorithm. Analysis was performed using Quantitative Gated SPECT (QGS) software. Within 2 weeks patients underwent cardiac magnetic resonance imaging (cMRI, 1.5-T unit CVi; GE Healthcare) using a 30-frame acquisition protocol and dedicated software for analysis (MASS 6.1; Medis).
resultsThe ventricular volumes obtained with 8-frame QGS showed excellent correlations with the cMRI volumes (end-diastolic volume (EDV), r = 0.90; end-systolic volume (ESV), r = 0.94; p < 0.001). However, QGS significantly underestimated the ventricular volumes (mean differences: EDV, -39.5 ± 29 mL; ESV, -15.4 ± 22 mL; p < 0.001). Similarly, the ventricular volumes obtained with 16-frame QGS showed an excellent correlations with the cMRI volumes (EDV, r = 0.92; ESV, r = 0.95; p < 0.001) but with significant underestimations (mean differences: EDV, -33.2 ± 26 mL; ESV, -17.9 ± 20 mL; p < 0.001). Despite significantly lower values (47.9 ± 16 % vs. 51.2 ± 15 %, p < 0.008), 8-frame QGS mean ejection fraction (EF) was closely correlated with the cMRI values (r = 0.84, p < 0.001). The mean EF with 16-frame QGS showed the best correlation with the cMRI values (r = 0.91, p < 0.001) and was similar to the mean cMRI value (49.6 ± 16 %, p not significant). Regional analysis showed a good correlation between both 8-frame and 16-frame QGS and cMRI wall motion score indexes (8-frame WMSI, r = 0.85; 16-frame WMSI, r = 0.89; p < 0.01).
conclusionLow-dose gated SPECT with a CZT camera provides ventricular volumes that correlate well with cMRI results despite significant underestimation in the measure values. EF estimation appeared to be more accurate with 16-frame reformatted images than with 8-frame images.
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