ArticleEpidemiology and psychiatric sciences2014
Insight, positive and negative symptoms, hope, depression and self-stigma: a comprehensive model of mutual influences in schizophrenia spectrum disorders.
Article in Epidemiology and psychiatric sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- The cognitive model of negative symptoms: a systematic review and meta-analysis of the dysfunctional belief systems associated with negative symptoms in schizophrenia spectrum disorders.Psychological medicine · 2025Pooled it
- Self-stigma in schizophrenia: a systematic review and meta-analysis of 37 studies from 25 high- and low-to-middle income countries.Molecular psychiatry · 2023Pooled it
- The Relationship Between Clinical and Personal Recovery in Patients With Schizophrenia Spectrum Disorders: A Systematic Review and Meta-analysis.Schizophrenia bulletin · 2018Pooled it
- Trial
- Article
- Longitudinal changes in personal recovery in individuals with psychotic disorders through hospitalisation in a psychiatric ward: preliminary findings.BMC psychiatry · 2021Article
- Support for the social-cognitive model of internalized stigma in serious mental illness.Journal of psychiatric research · 2021Article
- Longitudinal predictors of stigma in first-episode psychosis: Mediating effects of depression.Early intervention in psychiatry · 2021Article
- Article
- The Relationship between Basic Hope and Depression: Forgiveness as a Mediator.The Psychiatric quarterly · 2020Article
- Subjective Recovery in Patients with Schizophrenia and Related Factors.Community mental health journal · 2020Article
- Self-stigma in serious mental illness and autism spectrum disorder: Results from the REHABase national psychiatric rehabilitation cohort.European psychiatry : the journal of the Association of European Psychiatrists · 2020Article
- Mediation and moderation analyses: exploring the complex pathways between hope and quality of life among patients with schizophrenia.BMC psychiatry · 2020Article
- Insight and Symptom Severity in an Inpatient Psychiatric Sample.The Psychiatric quarterly · 2019Article
- Coping Strategies for Oral Health Problems by People with Schizophrenia.Translational neuroscience · 2019Article
- Insight, self-stigma and psychosocial outcomes in Schizophrenia: a structural equation modelling approach.Epidemiology and psychiatric sciences · 2018Article
- Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018Article
- Quality of life, self-stigma, and hope in schizophrenia spectrum disorders: a cross-sectional study.Neuropsychiatric disease and treatment · 2017Article
- Comorbidity of schizophrenia and social phobia - impact on quality of life, hope, and personality traits: a cross sectional study.Neuropsychiatric disease and treatment · 2017Article
- The "Insight Paradox" in Schizophrenia: Magnitude, Moderators and Mediators of the Association Between Insight and Depression.Schizophrenia bulletin · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims. Insight, positive and negative symptoms, hope, depression and self-stigma are relevant variables in schizophrenia spectrum disorders. So far, research on their mutual influences has been patchy. This study simultaneously tests the associations between these variables. Methods. A total of 284 people with schizophrenia spectrum disorders were assessed using the Schedule for the Assessment of Insight, Positive and Negative Syndrome Scale, Integrative Hope Scale, Centre for Epidemiological Studies Depression Scale and Internalized Stigma of Mental Illness scale. Path analysis was applied to test the hypothesized relationships between the variables. Results. Model support was excellent. Strong and mutual causal influences were confirmed between hope, depression and self-stigma. The model supported the assumption that insight diminishes hope and increases depression and self-stigma. While negative symptoms directly affected these three variables, reducing hope and increasing depression and self-stigma, positive symptoms did not. However, positive symptoms diminished self-stigma on a pathway via insight. Conclusions. This study provides a comprehensive synopsis of the relationships between six variables relevant for schizophrenia spectrum disorders. Research implications include the need to investigate determinants of consequences of insight, and the sequence of influences exerted by positive and negative symptoms. Clinical implications include the importance of interventions against self-stigma and of taking a contextualized approach to insight.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.