ArticleFrontiers in neuroscience2013
Perception of stochastically undersampled sound waveforms: a model of auditory deafferentation.
Article in Frontiers in neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
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Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of age and noise exposure history on auditory nerve response amplitudes: A systematic review, study, and meta-analysis.Hearing research · 2024Pooled it
- Detecting Noise-Induced Cochlear Synaptopathy by Auditory Brainstem Response in Tinnitus Patients With Normal Hearing Thresholds: A Meta-Analysis.Frontiers in neuroscience · 2021Pooled it
- Neural and behavioral changes after the use of hearing aids.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2018Trial
- Temporal integration in the subcortical auditory system and behavioral evidence of its dysfunction after "temporary" noise-induced hearing loss.bioRxiv : the preprint server for biology · 2026Article
- Predicting Cochlear Synaptopathy in Mice with Varying Degrees of Outer Hair Cell Dysfunction Using Auditory Evoked Potentials.Journal of the Association for Research in Otolaryngology : JARO · 2026Article
- Short-term hearing aid use reduces auditory cortical responses to speech-in-noise listening among older adults with age-related hearing loss.Frontiers in aging neuroscience · 2026Article
- Deciphering Compromised Speech-in-Noise Intelligibility in Older Listeners: The Role of Cochlear Synaptopathy.eNeuro · 2025Article
- Cochlear Synaptopathy Evaluation With Electrocochleography in Patients With Hearing Difficulty in Noise Despite Normal Hearing Levels.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025Article
- Modeling the impact of cochlear nerve degeneration on speech recognition performance.PloS one · 2025Article
- Hierarchical differences in the encoding of amplitude modulation in the subcortical auditory system of awake nonhuman primates.Journal of neurophysiology · 2024Article
- Spectral degradation and carrier sentences increase age-related temporal processing deficits in a cue-specific manner.The Journal of the Acoustical Society of America · 2024Article
- Effects of Age and Noise Exposure History on Auditory Nerve Response Amplitudes: A Systematic Review, Study, and Meta-Analysis.bioRxiv : the preprint server for biology · 2024Article
- Normal behavioral discrimination of envelope statistics in budgerigars with kainate-induced cochlear synaptopathy.Hearing research · 2024Article
- Computational modeling of the human compound action potential.The Journal of the Acoustical Society of America · 2023Article
- An overview of the HASPI and HASQI metrics for predicting speech intelligibility and speech quality for normal hearing, hearing loss, and hearing aids.Hearing research · 2022Review
- MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea.Life science alliance · 2022Article
- Animal models of hidden hearing loss: Does auditory-nerve-fiber loss cause real-world listening difficulties?Molecular and cellular neurosciences · 2022Review
- Neural Presbyacusis in Humans Inferred from Age-Related Differences in Auditory Nerve Function and Structure.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Aging Effects on Cortical Responses to Tones and Speech in Adult Cochlear-Implant Users.Journal of the Association for Research in Otolaryngology : JARO · 2021Article
- Understanding degraded speech leads to perceptual gating of a brainstem reflex in human listeners.PLoS biology · 2021Article
Corrections and comments
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Auditory deafferentation, or permanent loss of auditory nerve afferent terminals, occurs after noise overexposure and aging and may accompany many forms of hearing loss. It could cause significant auditory impairment but is undetected by regular clinical tests and so its effects on perception are poorly understood. Here, we hypothesize and test a neural mechanism by which deafferentation could deteriorate perception. The basic idea is that the spike train produced by each auditory afferent resembles a stochastically digitized version of the sound waveform and that the quality of the waveform representation in the whole nerve depends on the number of aggregated spike trains or auditory afferents. We reason that because spikes occur stochastically in time with a higher probability for high- than for low-intensity sounds, more afferents would be required for the nerve to faithfully encode high-frequency or low-intensity waveform features than low-frequency or high-intensity features. Deafferentation would thus degrade the encoding of these features. We further reason that due to the stochastic nature of nerve firing, the degradation would be greater in noise than in quiet. This hypothesis is tested using a vocoder. Sounds were filtered through ten adjacent frequency bands. For the signal in each band, multiple stochastically subsampled copies were obtained to roughly mimic different stochastic representations of that signal conveyed by different auditory afferents innervating a given cochlear region. These copies were then aggregated to obtain an acoustic stimulus. Tone detection and speech identification tests were performed by young, normal-hearing listeners using different numbers of stochastic samplers per frequency band in the vocoder. Results support the hypothesis that stochastic undersampling of the sound waveform, inspired by deafferentation, impairs speech perception in noise more than in quiet, consistent with auditory aging effects.
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