ArticleNutrition and metabolic insights2012
A finished dietary supplement stimulates lipolysis and metabolic rate in young men and women.
Article in Nutrition and metabolic insights, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Physiological and pharmacokinetic effects of oral 1,3-dimethylamylamine administration in men.BMC pharmacology & toxicology · 2013Trial
- Boost Me: Prevalence and Reasons for the Use of Stimulant Containing Pre Workout Supplements Among Fitness Studio Visitors in Mainz (Germany).Frontiers in psychology · 2018Article
- Effect of novel dietary supplement on metabolismJournal of traditional and complementary medicine · 2017Article
- Effects of controlled doses of Oxyelite Pro on physical performance in rats.Nutrition & metabolism · 2016Article
- Acute stimulant ingestion and neurocognitive performance in healthy participants.Journal of athletic training · 2015Article
- Article
- Treatment of human muscle cells with popular dietary supplements increase mitochondrial function and metabolic rate.Nutrition & metabolism · 2012Article
- Impact of a dietary supplement containing 1,3-dimethylamylamine on blood pressure and bloodborne markers of health: a 10-week intervention study.Nutrition and metabolic insights · 2012Article
- Biochemical and anthropometric effects of a weight loss dietary supplement in healthy men and women.Nutrition and metabolic insights · 2012Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDietary supplements are often marketed to increase lipolysis and thermogenesis, with the proposed end result being weight loss and body fat reduction. It was the purpose of the present investigation to study the acute effects of a weight/fat loss supplement within a sample of healthy human subjects.
methodsTwelve subjects (men 24.8 ± 4.3 yrs; women 22.8 ± 0.4 yrs) ingested a dietary supplement (OxyELITE Pro™) or a placebo, on two separate days in a double-blind, cross-over design. Blood samples were collected immediately before ingestion, and at 60 and 120 minutes post ingestion, and analyzed for plasma glycerol and free fatty acids (FFA). Breath samples were collected immediately before ingestion and at 30, 60, 90, and 120 minutes post ingestion, for a measure of kilocalorie expenditure using indirect calorimetry. Area under the curve (AUC) was calculated. Heart rate and blood pressure were recorded at all times and rate pressure product (RPP) was calculated.
resultsAUC was greater for supplement compared to placebo for glycerol (22.74 ± 1.98 μg · mL(-1) · 2 hr(-1) vs. 15.76 ± 1.36 μg · mL(-1) · 2 hr(-1); P = 0.001), FFA (1.62 ± 0.07 mmol · L(-1) · 2 hr(-1) vs. 0.78 ± 0.12 mmol · L(-1) · 2 hr(-1); P < 0.0001), and kilocalorie expenditure (149 ± 7 kcal · 2 hr(-1) vs. 122 ± 8 kcal · 2 hr(-1); P = 0.005). Heart rate (P = 0.02), systolic blood pressure (P < 0.0001), and RPP (P = 0.002) were higher for supplement compared to placebo.
conclusionIngestion of OxyELITE Pro™ resulted in an increase in blood markers of lipolysis, as well as metabolic rate, during a two-hour post ingestion time period. An increase in hemodynamic variables was also observed. These findings are in reference to a sample of healthy men and women who were naïve to treatment with the dietary supplement. Additional work is needed to determine if the acute changes observed here would persist with chronic use of the supplement and possibly lead to weight/body fat loss over time.
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