Insulin therapy and cancer.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

1. Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence.Breast cancer research : BCR · 2015
   Pooled it
2. Pharmacologic Therapy of Diabetes and Overall Cancer Risk and Mortality: A Meta-Analysis of 265 Studies.Scientific reports · 2015 · on this map
   Pooled it
3. Use of insulin and insulin analogs and risk of cancer - systematic review and meta-analysis of observational studies.Current drug safety · 2013
   Pooled it
4. A disproportionality analysis of insulin glargine in the overall population and in pregnant women using the FDA adverse event reporting system (FAERS) database.PloS one · 2025
   Article
5. Anti-Diabetic Therapies and Cancer: From Bench to Bedside.Biomolecules · 2024
   Review
6. The skeleton: an overlooked regulator of systemic glucose metabolism in cancer?Frontiers in oncology · 2024
   Article
7. The Effects of 6 Common Antidiabetic Drugs on Anti-PD1 Immune Checkpoint Inhibitor in Tumor Treatment.Journal of immunology research · 2022
   Article
8. Insulin reverses choriocarcinoma 5- fluorouracil resistance.Bioengineered · 2021
   Article
9. Diabetes and Cancer: Risk, Challenges, Management and Outcomes.Cancers · 2021
   Review
10. Hyperinsulinemia in Obesity, Inflammation, and Cancer.Diabetes & metabolism journal · 2021
    Review
11. Targeting Adipokines in Obesity-Related Tumors.Frontiers in oncology · 2021
    Review
12. Emerging Kinase Therapeutic Targets in Pancreatic Ductal Adenocarcinoma and Pancreatic Cancer Desmoplasia.International journal of molecular sciences · 2020
    Review
13. The Impact of Diabetes Mellitus on the Second Primary Malignancies in Colorectal Cancer Patients.Frontiers in oncology · 2020
    Article
14. Transcriptomic Analyses and Potential Therapeutic Targets of Pancreatic Cancer With Concomitant Diabetes.Frontiers in oncology · 2020
    Article
15. Anti-Diabetic Drugs: Cure or Risk Factors for Cancer?Pathology oncology research : POR · 2018
    Review
16. Oncogenic activity of insulin in the development of non-small cell lung carcinoma.Oncology letters · 2018
    Article
17. Favourable changes in mortality in people with diabetes: US NHANES 1999-2010.Diabetes, obesity & metabolism · 2018
    Article
18. Diabetes Mellitus and Risk of Colorectal Cancer Mortality in Japan: the Japan Collaborative Cohort StudyAsian Pacific journal of cancer prevention : APJCP · 2016
    Article
19. Insulin glargine use and breast cancer risk: Associations with cumulative exposure.Acta oncologica (Stockholm, Sweden) · 2016
    Article
20. Impact of Diabetes Status and Medication on Presentation, Treatment, and Outcome of Stage II Colon Cancer Patients.Journal of cancer epidemiology · 2015
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as