Evidence map›Paper›PMID 23881402›Full record

ArticleScientific reports2013

Competitive binding of natural amphiphiles with graphene derivatives.

Slaven Radic, Nicholas K Geitner, Ramakrishna Podila, Aleksandr Käkinen, Pengyu Chen, Pu Chun Ke, Feng Ding

Abstract read
In one paragraph

Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. NanoEHS beyond Toxicity - Focusing on Biocorona.Environmental science. Nano · 2017
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Slaven RadicDepartment of Physics and Astronomy, COMSET, Clemson University, Clemson, South Carolina 29634, USA.
Nicholas K Geitner
Ramakrishna Podila
Aleksandr Käkinen
Pengyu Chen
Pu Chun Ke
Feng Ding

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the transformation of graphene derivatives by natural amphiphiles is essential for elucidating the biological and environmental implications of this emerging class of engineered nanomaterials. Using rapid discrete-molecular-dynamics simulations, we examined the binding of graphene and graphene oxide with peptides, fatty acids, and cellulose, and complemented our simulations by experimental studies of Raman spectroscopy, FTIR, and UV-Vis spectrophotometry. Specifically, we established a connection between the differential binding and the conformational flexibility, molecular geometry, and hydrocarbon content of the amphiphiles. Importantly, our dynamics simulations revealed a Vroman-like competitive binding of the amphiphiles for the graphene oxide substrate. This study provides a mechanistic basis for addressing the transformation, evolution, transport, biocompatibility, and toxicity of graphene derivatives in living systems and the natural environment.

Indexed as

Binding, CompetitiveGraphiteMolecular ConformationMolecular Dynamics SimulationNanostructuresOxidesSpectroscopy, Fourier Transform InfraredSpectrum Analysis, RamanSurface-Active AgentsTemperatureThermodynamicsGraphiteOxidesSurface-Active Agents

Identifiers

PMID23881402
PMCPMC3721079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.