Evidence map›Paper›PMID 23881187›Full record

Trial reportAIDS and behavior2013

A peer-educator network HIV prevention intervention among injection drug users: results of a randomized controlled trial in St. Petersburg, Russia.

Irving F Hoffman, Carl A Latkin, Polina V Kukhareva, Sergey V Malov, Julia V Batluk, Alla V Shaboltas, Roman V Skochilov, Nicolay V Sokolov, Sergei V Verevochkin, Michael G Hudgens and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 6 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Irving F HoffmanDivision of Infectious Diseases, Department of Medicine, UNC Hospitals, University of North Carolina, CB # 7030, Chapel Hill, NC, 27599, USA. hoffmani@med.unc.edu
Carl A Latkin
Polina V Kukhareva
Sergey V Malov
Julia V Batluk
Alla V Shaboltas
Roman V Skochilov
Nicolay V Sokolov
Sergei V Verevochkin
Michael G Hudgens
Andrei P Kozlov

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
The Impact of Neighborhoods, Networks and Depression on Drug Users' HIV RisksR01DA022961 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LATKIN, CARL A · 2007 to 2011
$3.0M
RCT of Russian IDU Peer Network HIV Prevent InterventionR01DA016142 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LATKIN, CARL A · 2003 to 2007
$2.5M
NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI50410NIDA NIH HHS R01 DA016142NIDA NIH HHS R01 DA022961
6 · The paper itself

Abstract

We evaluated the efficacy of a peer-educator network intervention as a strategy to reduce HIV acquisition among injection drug users (IDUs) and their drug and/or sexual networks. A randomized controlled trial was conducted in St. Petersburg, Russia among IDU index participants and their risk network participants. Network units were randomized to the control or experimental intervention. Only the experimental index participants received training sessions to communicate risk reduction techniques to their network members. Analysis includes 76 index and 84 network participants who were HIV uninfected. The main outcome measure was HIV sero-conversion. The incidence rates in the control and experimental groups were 19.57 (95 % CI 10.74-35.65) and 7.76 (95 % CI 3.51-17.19) cases per 100 p/y, respectively. The IRR was 0.41 (95 % CI 0.15-1.08) without a statistically significant difference between the two groups (log rank test statistic X(2) = 2.73, permutation p value = 0.16). Retention rate was 67 % with a third of the loss due to incarceration or death. The results show a promising trend that this strategy would be successful in reducing the acquisition of HIV among IDUs.

Indexed as

Health EducationPeer GroupAdultAIDS SerodiagnosisBlotting, WesternCommunicationCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleFollow-Up StudiesHIV InfectionsHIV SeronegativityHumansMaleRisk Reduction BehaviorRussia

Identifiers

PMID23881187
PMCPMC3950300

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.