Evidence map›Paper›PMID 23880931›Full record

ReviewMarine drugs2013

Marine pharmacology in 2009-2011: marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action.

Alejandro M S Mayer, Abimael D Rodríguez, Orazio Taglialatela-Scafati, Nobuhiro Fusetani

Abstract readReview
In one paragraph

Review in Marine drugs, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. Capnellenes fromPharmaceuticals (Basel, Switzerland) · 2023
    Article

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alejandro M S MayerDepartment of Pharmacology, Chicago College of Osteopathic Medicine, Midwestern University, 555 31st Street, Downers Grove, Illinois 60515, USA. amayer@midwestern.edu
Abimael D Rodríguez
Orazio Taglialatela-Scafati
Nobuhiro Fusetani

Funding

New Leads Against Cancer and Infectious Diseases from Puerto Rican Reef SpeciesSC1GM086271 · NIGMS · UNIVERSITY OF PUERTO RICO RIO PIEDRAS · PI RODRIGUEZ, ABIMAEL D · 2010 to 2013
$1.2M
NIGMS NIH HHS 1SC1GM086271-01A1NIGMS NIH HHS SC1 GM086271
6 · The paper itself

Abstract

The peer-reviewed marine pharmacology literature from 2009 to 2011 is presented in this review, following the format used in the 1998-2008 reviews of this series. The pharmacology of structurally-characterized compounds isolated from marine animals, algae, fungi and bacteria is discussed in a comprehensive manner. Antibacterial, antifungal, antiprotozoal, antituberculosis, and antiviral pharmacological activities were reported for 102 marine natural products. Additionally, 60 marine compounds were observed to affect the immune and nervous system as well as possess antidiabetic and anti-inflammatory effects. Finally, 68 marine metabolites were shown to interact with a variety of receptors and molecular targets, and thus will probably contribute to multiple pharmacological classes upon further mechanism of action studies. Marine pharmacology during 2009-2011 remained a global enterprise, with researchers from 35 countries, and the United States, contributing to the preclinical pharmacology of 262 marine compounds which are part of the preclinical pharmaceutical pipeline. Continued pharmacological research with marine natural products will contribute to enhance the marine pharmaceutical clinical pipeline, which in 2013 consisted of 17 marine natural products, analogs or derivatives targeting a limited number of disease categories.

Indexed as

AnimalsAnti-Bacterial AgentsAntifungal AgentsAnti-Inflammatory AgentsAntiprotozoal AgentsAntitubercular AgentsAntiviral AgentsAquatic OrganismsBiological FactorsHumansHypoglycemic AgentsImmune SystemNervous SystemAnti-Bacterial AgentsAntifungal AgentsAnti-Inflammatory AgentsAntiprotozoal AgentsAntitubercular AgentsAntiviral AgentsBiological FactorsHypoglycemic Agents

Identifiers

PMID23880931
PMCPMC3736438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.