Evidence map›Paper›PMID 23880379›Full record

ArticleDevelopment and psychopathology2013

Vulnerability to depression: a moderated mediation model of the roles of child maltreatment, peer victimization, and serotonin transporter linked polymorphic region genetic variation among children from low socioeconomic status backgrounds.

Adrienne M Banny, Dante Cicchetti, Fred A Rogosch, Assaf Oshri, Nicki R Crick

Open access · greenAbstract read
In one paragraph

Article in Development and psychopathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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  14. Hippocampal Subfields Volume Reduction in High Schoolers with Previous Verbal Abuse Experiences.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adrienne M BannyUniversity of Minnesota, Minneapolis, MN, USA. banny001@umn.edu
Dante Cicchetti
Fred A Rogosch
Assaf Oshri
Nicki R Crick
University of Rochester · USUniversity of Minnesota System · US

Funding

Chronic Stress of Maltreatment: Drug Use VulnerabilityR01DA017741 · NIDA · UNIVERSITY OF ROCHESTER · PI CICCHETTI, DANTE CICCHETTI, ROGOSCH, FRED A · 2004 to 2016
$5.1M
Child Abuse and Trauma Related Psychopathology: Multiple Levels of AnalysisR01MH083979 · NIMH · UNIVERSITY OF ROCHESTER · PI CICCHETTI, DANTE CICCHETTI, ROGOSCH, FRED A · 2009 to 2013
$3.2M
TEEN DRUG USE/ABUSE: PATHWAYS FROM CHILD MALTREATMENTR01DA012903 · NIDA · UNIVERSITY OF ROCHESTER · PI CICCHETTI, DANTE · 2000 to 2004
$2.2M
PREVENTIVE INTERVENTION FOR MALTREATED INFANTSR01MH054643 · NIMH · UNIVERSITY OF ROCHESTER · PI CICCHETTI, DANTE · 1998 to 2002
$2.2M
NIDA NIH HHS DA12903NIDA NIH HHS DA17741NIDA NIH HHS R01 DA012903NIDA NIH HHS R01 DA017741NIMH NIH HHS R01 MH054643NIMH NIH HHS R01 MH083979
6 · The paper itself

Abstract

Child maltreatment, peer victimization, and a polymorphism of the serotonin transporter gene (5-HTTLPR) were examined as predictors of depressive symptomatology. Children (M age = 11.26, SD = 1.65), including 156 maltreated and 145 nonmaltreated children from comparable low socioeconomic backgrounds, provided DNA samples and self-reports of relational peer victimization, overt peer victimization, and depressive symptoms. Path analysis showed that relational and overt victimization mediated the association between child maltreatment and depressive symptoms. Bootstrapping procedures were used to test moderated mediation and demonstrated that genotype moderated the indirect effects of relational and overt victimization on child depressive symptoms, such that victimized children with the long/long variation were at an increased risk for depressive symptoms compared to victimized children carrying a short allele. Results highlight the utility of examining process models that incorporate biological and psychological factors contributing to the development of depressive symptomatology and provide direction toward understanding and promoting resilience among high-risk youth from a multiple levels of analysis approach.

Indexed as

Disease SusceptibilityAdolescentChildChild AbuseCrime VictimsDepressionDepressive DisorderFemaleGenetic VariationHumansMaleModels, PsychologicalPeer GroupPolymorphism, GeneticSerotonin Plasma Membrane Transport ProteinsSocial ClassSerotonin Plasma Membrane Transport Proteins

Identifiers

PMID23880379
PMCPMC3959105
OpenAlexW2118304065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.