ArticleAnnals of human biology
Is orbital volume associated with eyeball and visual cortex volume in humans?
Article in Annals of human biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Cranial Modularity and Integration in Modern Humans: Evidence for Regional Variability and Evolutionary Flexibility.American journal of biological anthropology · 2026Article
- Measuring differences in the ERG in myopia using the RETeval device with skin electrodes.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Prediction of exophthalmos by body mass index for craniofacial reconstruction: consequences for cold cases.Forensic science, medicine, and pathology · 2024Article
- Postnatal growth and spatial conformity of the cranium, brain, eyeballs and masseter muscles in the macaque (Macaca mulatta).Journal of anatomy · 2023Article
- Associations Between Regional Environment and Cornea-Related Morphology of the Eye in Young Adults: A Large-Scale Multicenter Cross-Sectional Study.Investigative ophthalmology & visual science · 2021Article
- Assessment of Orbital Computed Tomography (CT) Imaging Biomarkers in Patients with Thyroid Eye Disease.Journal of digital imaging · 2019Article
- Imaging biomarkers in thyroid eye disease and their clinical associations.Journal of medical imaging (Bellingham, Wash.) · 2018Article
- Primary visual cortex in neandertals as revealed from the occipital remains from the El Sidrón site, with emphasis on the new SD-2300 specimen.Journal of anatomy · 2018Article
- Brain size affects performance in a reversal-learning test.Proceedings. Biological sciences · 2018Article
- How neuroscience can inform the study of individual differences in cognitive abilities.Reviews in the neurosciences · 2017Review
- Structural-Functional Relationships Between Eye Orbital Imaging Biomarkers and Clinical Visual Assessments.Proceedings of SPIE--the International Society for Optical Engineering · 2017Article
- Structural Functional Associations of the Orbit in Thyroid Eye Disease: Kalman Filters to Track Extraocular Rectal Muscles.Proceedings of SPIE--the International Society for Optical Engineering · 2016Article
- Patterns of Individual Variation in Visual Pathway Structure and Function in the Sighted and Blind.PloS one · 2016Article
- Analysis of the volumetric relationship among human ocular, orbital and fronto-occipital cortical morphology.Journal of anatomy · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundIn humans orbital volume increases linearly with absolute latitude. Scaling across mammals between visual system components suggests that these larger orbits should translate into larger eyes and visual cortices in high latitude humans. Larger eyes at high latitudes may be required to maintain adequate visual acuity and enhance visual sensitivity under lower light levels.
aimTo test the assumption that orbital volume can accurately index eyeball and visual cortex volumes specifically in humans. SUBJECTS AND
methodsStructural Magnetic Resonance Imaging (MRI) techniques are employed to measure eye and orbit (n = 88) and brain and visual cortex (n = 99) volumes in living humans. Facial dimensions and foramen magnum area (a proxy for body mass) were also measured.
resultsA significant positive linear relationship was found between (i) orbital and eyeball volumes, (ii) eyeball and visual cortex grey matter volumes and (iii) different visual cortical areas, independently of overall brain volume.
conclusionIn humans the components of the visual system scale from orbit to eye to visual cortex volume independently of overall brain size. These findings indicate that orbit volume can index eye and visual cortex volume in humans, suggesting that larger high latitude orbits do translate into larger visual cortices.
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