ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2013
Prevalence and prognostic value of conduction disturbances at the time of diagnosis of cardiac AL amyloidosis.
Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 54 citations in OpenAlex.
- A Comprehensive Review of the Management of Light-Chain (AL) and Transthyretin (ATTR) Cardiac Amyloidosis.Reviews in cardiovascular medicine · 2025Review
- Electrocardiographic Patterns and Arrhythmias in Cardiac Amyloidosis: From Diagnosis to Therapeutic Management-A Narrative Review.Journal of clinical medicine · 2024Review
- Arrhythmic Risk Stratification in Cardiac Amyloidosis: A Review of the Current Literature.Journal of cardiovascular development and disease · 2024Review
- Management of Arrhythmias and Conduction Disorders in Amyloid Cardiomyopathy.Journal of clinical medicine · 2024Review
- Prognostic Value of Holter Monitoring in Light Chain Amyloidosis.Journal of clinical medicine · 2023Article
- Arrhythmias in Patients with Cardiac Amyloidosis: A Comprehensive Review on Clinical Management and Devices.Journal of cardiovascular development and disease · 2023Review
- Sustained ventricular arrhythmia and sinus node dysfunction revealing a cardiac amyloidosis: A case report.Annals of medicine and surgery (2012) · 2022Article
- Clinical management of amyloid cardiomyopathy.Heart failure reviews · 2022Review
- New Advanced Imaging Parameters and Biomarkers-A Step Forward in the Diagnosis and Prognosis of TTR Cardiomyopathy.Journal of clinical medicine · 2022Review
- Diagnosis and treatment of cardiac amyloidosis: an interdisciplinary consensus statement.Wiener klinische Wochenschrift · 2020Article
- Noninvasive Mapping of the Electrophysiological Substrate in Cardiac Amyloidosis and Its Relationship to Structural Abnormalities.Journal of the American Heart Association · 2019Article
- Direct Current Cardioversion of Atrial Arrhythmias in Adults With Cardiac Amyloidosis.Journal of the American College of Cardiology · 2019Article
- New and Evolving Concepts Regarding the Prognosis and Treatment of Cardiac Amyloidosis.Current heart failure reports · 2016Review
- Recent advances in the noninvasive strategies of cardiac amyloidosis.Heart failure reviews · 2016Review
- Role of imaging in the diagnosis and management of patients with cardiac amyloidosis: state of the art review and focus on emerging nuclear techniques.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Review
- [Cardiac arrhythmias and amyloidosis].Archivos peruanos de cardiologia y cirugia cardiovascularReview
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeTo evaluate the prevalence and the prognostic implications of conduction delays in a large cohort of cardiac AL patients.
methodsEcho Doppler and 12-lead ECG were collected in 344 consecutive patients in whom diagnosis of AL amyloidosis was concluded between 2008 and 2010. Patients were subdivided according to the presence (n = 240) or absence (n = 104) of cardiac involvement.
resultsWhen compared with patients without myocardial involvement, cardiac AL was associated with prolonged PQ, QRS, QT and QTc intervals (P < 0.05), and with higher prevalence of intraventricular blocks (27.5% vs. 16.5%, P < 0.05), that was associated with higher wall thickness, worse diastolic and regional systolic function, higher NT-proBNP values (all P < 0.05), and higher mortality (P = 0.0001; median follow-up: 402 days).
conclusionIntraventricular conduction delays have a negative prognostic impact in patients with cardiac AL amyloidosis. Their presence should not be overlooked in the diagnostic workup, prompting a more accurate cardiological support.
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