Evidence map›Paper›PMID 23878613›Full record

ArticleClinical practice and epidemiology in mental health : CP & EMH2013

Epidemiology of early-onset dementia: a review of the literature.

Renata Teles Vieira, Leonardo Caixeta, Sergio Machado, Adriana Cardoso Silva, Antonio Egidio Nardi, Oscar Arias-Carrión, Mauro Giovanni Carta

Open access · hybridAbstract read
In one paragraph

Article in Clinical practice and epidemiology in mental health : CP & EMH, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed, 7 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 7 syntheses or guidelines pooled it, 319 citations in OpenAlex.

  1. Pooled it
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  6. Pooled it
  7. Pooled it
  8. Mapping the Young-Onset Dementia Research in the Asia-Pacific Region: A Scoping Review.Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists · 2026
    Article
  9. Association between unhealthy lifestyles and young-onset dementia: a nationwide cohort study.European archives of psychiatry and clinical neuroscience · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The enigma of vascular dementia: current state and emerging perspectives.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  16. Article
  17. Article
  18. Article
  19. Public attitudes toward dementia risk prediction: A mixed-methods study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  20. Review

80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Renata Teles VieiraDementia Outpatient Unit, Hospital of the Clinics, Federal University of Goiás, Brazil.
Leonardo Caixeta
Sergio Machado
Adriana Cardoso Silva
Antonio Egidio Nardi
Oscar Arias-Carrión
Mauro Giovanni Carta
Universidade Federal de Goiás · BRUniversidade Federal do Rio de Janeiro · BRUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Presenile Dementia or Early Onset Dementia (EOD) is a public health problem, it differs from Senile Dementia, and encloses a significant number of cases; nevertheless, it is still poorly understood and underdiagnosed. This study aims to review the prevalence and etiology of EOD, comparing EOD with Senile Dementia, as well as to show the main causes of EOD and their prevalence in population and non-population based studies. The computer-supported search used the following databases: Pubmed/Medline, ISI Web of Knowledge and Scielo. The search terms were alcohol-associated dementia, Alzheimer's disease, dementia, Creutzfeldt-jakob disease, dementia with lewy bodies, early onset dementia, frontotemporal lobar degeneration, Huntington's disease, mixed dementia, neurodegenerative disorders, Parkinson's disease dementia, presenile dementia, traumatic brain injury, vascular dementia. Only papers published in English and conducted from 1985 up to 2012 were preferentially reviewed. Neurodegenerative diseases are the most common etiologies seen in EOD. Among the general population, the prevalence of EOD was found to range between 0 to 700 per 100.000 habitants in groups of 25-64 years old, with an increasing incidence with age. The progression of EOD was found to range between 8.3 to 22.8 new cases per 100.000 in those aged under 65 years. Alzheimer's disease (AD) is the major etiology, followed by Vascular Dementia (VaD) and Frontotemporal Lobar Degeneration (FTLD). A larger number of epidemiological studies to elucidate how environmental issues contribute to EOD are necessary, thus, we can collaborate in the planning and prevention of services toward dementia patients.

Indexed as

ADAlzheimer’s diseaseEarly Onset DementiaEODEpidemiologyFrontotemporal Lobar DegenerationFTLDNeurodegenerative DisordersPresenile DementiaVaD.Vascular Dementia

Identifiers

PMID23878613
PMCPMC3715758
OpenAlexW2049309389

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.