ArticleEvidence-based complementary and alternative medicine : eCAM2013
Chinese herbal medicine qi ju di huang wan for the treatment of essential hypertension: a systematic review of randomized controlled trials.
Article in Evidence-based complementary and alternative medicine : eCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Effects and safety of Chinese herbal medicine on inflammatory biomarkers in cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2022Pooled it
- Songling Xuemaikang Capsule () for primary hypertension: A systematic review of randomized controlled trials.Chinese journal of integrative medicine · 2015Pooled it
- Lung function benefits of traditional Chinese medicine Qiju granules against fine particulate air pollution exposure: a randomized controlled trial.Frontiers in medicine · 2024Article
- Traditional Chinese Medicine for Essential Hypertension: A Clinical Evidence Map.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Quality Control and Variability Assessment of an Eight-Herb Formulation for Hypertension Using Method Validation and Statistical Analysis.Molecules (Basel, Switzerland) · 2019Article
- The role of psychosocial determinants in predicting adherence to treatment in patient with hypertension.Interventional medicine & applied science · 2019Article
- Therapeutic Effect ofFrontiers in pharmacology · 2018Article
- Developing clinical practice guidelines for the integration of Chinese medicine and biomedicine: A new process.European journal of integrative medicine · 2016Article
- Hypertension from the perspective of Iranian traditional medicine.Iranian Red Crescent medical journal · 2014Article
- Protective effects of panax notoginseng saponins on cardiovascular diseases: a comprehensive overview of experimental studies.Evidence-based complementary and alternative medicine : eCAM · 2014Review
- Effectiveness of Stimulation of Acupoint KI 1 by Artemisia vulgaris (Moxa) for the Treatment of Essential Hypertension: A Systematic Review of Randomized Controlled Trials.Evidence-based complementary and alternative medicine : eCAM · 2014Review
- Is it a new approach for treating senile hypertension with kidney-tonifying chinese herbal formula? A systematic review of randomized controlled trials.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Traditional chinese medicine syndromes for essential hypertension: a literature analysis of 13,272 patients.Evidence-based complementary and alternative medicine : eCAM · 2014Review
- Chinese herbal medicine for the treatment of prehypertension.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Chinese herbal medicine for the treatment of obesity-related hypertension.Evidence-based complementary and alternative medicine : eCAM · 2013Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Chinese herbs are potentially effective for hypertension. Qi Ju Di Huang Wan (QJDHW) is a commonly used Chinese herbal medicine as a monotherapy or in combination with other antihypertensive agents for the treatment of essential hypertension (EH). However, there is no critically appraised evidence such as systematic reviews or meta-analyses on the effectiveness and safety of QJDHW for EH. Methods and Findings. CENTRAL, PubMed, CBM, CNKI, VIP, and online clinical trial registry websites were searched for published and unpublished randomized controlled trials (RCTs) of QJDHW for essential hypertension up to January 2013 with no language restrictions. A total of 10 randomized trials involving 1024 patients were included. Meta-analysis showed that QJDHW combined with antihypertensive drugs was more effective in lowering blood pressure and improving TCM syndrome for the treatment of essential hypertension than antihypertensive drugs used alone. No trials reported severe adverse events related to QJDHW. Conclusions. Our review suggests that QJDHW combined with antihypertensive drugs might be an effective treatment for lowering blood pressure and improving symptoms in patients with essential hypertension. However, the finding should be interpreted with caution because of the poor methodological quality of included trials. There is an urgent need for well-designed, long-term studies to assess the effectiveness of QJDHW in the treatment of essential hypertension.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.