ArticleJournal of allergy2013
The asthma phenotype in the obese: distinct or otherwise?
Article in Journal of allergy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Nutritional Interventions to Improve Asthma-Related Outcomes through Immunomodulation: A Systematic Review.Nutrients · 2020Pooled it
- Factors associated with having uncontrolled asthma in rural Appalachia.The Journal of asthma : official journal of the Association for the Care of Asthma · 2024Article
- Effects of biological therapies on patients with Type-2 high asthma and comorbid obesity.Frontiers in pharmacology · 2023Review
- Adiponectin and Asthma: Knowns, Unknowns and Controversies.International journal of molecular sciences · 2021Review
- Crosstalk Among Circadian Rhythm, Obesity and Allergy.International journal of molecular sciences · 2020Review
- Elucidation of causal direction between asthma and obesity: a bi-directional Mendelian randomization study.International journal of epidemiology · 2019Article
- Relationship of Allergy with Asthma: There Are More Than the Allergy "Eggs" in the Asthma "Basket".Frontiers in pediatrics · 2017Review
- Personalised medicine in asthma: from curative to preventive medicine.European respiratory review : an official journal of the European Respiratory Society · 2017Review
- Identifying biomarkers for asthma diagnosis using targeted metabolomics approaches.Respiratory medicine · 2016Article
- Metabolic Syndrome Is Associated with Increased Oxo-Nitrative Stress and Asthma-Like Changes in Lungs.PloS one · 2015Article
- Obesity and asthma: pathophysiology and implications for diagnosis and management in primary care.Experimental biology and medicine (Maywood, N.J.) · 2014Review
- Obesity, metabolic syndrome, and airway disease: a bioenergetic problem?Immunology and allergy clinics of North America · 2014Review
- What the Genetic Background of Individuals with Asthma and Obesity Can Reveal: Is β2-Adrenergic Receptor Gene Polymorphism Important?Pediatric allergy, immunology, and pulmonology · 2014Review
- The Advance of Personalized and Stratified Therapies in Bronchial Asthma: Phenotypes - Endotypes - Biomarkers.EJIFCC · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is a heterogenous disorder that can be classified into several different phenotypes. Recent cluster analyses have identified an "obese-asthma" phenotype which is characterized by late onset, female predominance and lack of atopy. In addition, obesity among early-onset asthmatics clearly exists and heightens the clinical presentation. Observational studies have demonstrated that asthma among the obese has a clinical presentation that is more severe, harder to control, and is not as responsive to standard controller therapies. While weight loss studies have demonstrated improvement in asthma outcomes, further studies need to be performed. The current knowledge of the existence of two obesity-asthma phenotypes (early- versus late-onset asthma) should encourage investigators to study these entities separately since just as they have distinct presentations, their course, response to therapies, and weight loss strategies may be different as well.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.