ArticleBMC neurology2013
Internal jugular venous abnormalities in transient monocular blindness.
Article in BMC neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- A proposed framework for cerebral venous congestion.The neuroradiology journal · 2022Article
- Cerebrospinal fluid dynamics coupled to the global circulation in holistic setting: Mathematical models, numerical methods and applications.International journal for numerical methods in biomedical engineering · 2022Article
- Retrograde blood flow in the internal jugular veins of humans with hypertension may have implications for cerebral arterial blood flow.European radiology · 2020Observational
- Transient Global Amnesia Linked to Impairment of Brain Venous Drainage: An Ultrasound Investigation.Frontiers in neurology · 2019Article
- Understanding jugular venous outflow disturbance.CNS neuroscience & therapeutics · 2018Review
- Neck Vessel Cross-Sectional Area Measured with MRI: Scan-Rescan Reproducibility for Longitudinal Evaluations.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2018Article
- Ultrasound diagnosis of transverse sinus hypoplasia using flow profiles of the internal jugular vein.PloS one · 2017Article
- Article
- Assessment of Internal Jugular Vein Size in Healthy Subjects with Magnetic Resonance and Semiautomatic Processing.Behavioural neurology · 2016Article
- An anatomy-based lumped parameter model of cerebrospinal venous circulation: can an extracranial anatomical change impact intracranial hemodynamics?BMC neurology · 2015Article
- Article
- Microgravity-induced fluid shift and ophthalmic changes.Life (Basel, Switzerland) · 2014Review
- Is there a link between the extracranial venous system and central nervous system pathology?BMC medicine · 2013Article
- A narrative review of retinal vascular parameters and the applications (Part II): Diagnosis in stroke.Brain circulationReview
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe etiology of transient monocular blindness (TMB) in patients without carotid stenosis has been linked to ocular venous hypertension, for their increased retrobulbar vascular resistance, sustained retinal venule dilatation and higher frequency of jugular venous reflux (JVR). This study aimed to elucidate whether there are anatomical abnormalities at internal jugular vein (IJV) in TMB patients that would contribute to impaired cerebral venous drainage and consequent ocular venous hypertension.
methodsContrast-enhanced axial T1-weighted magnetic resonance imaging (MRI) was performed in 23 TMB patients who had no carotid stenosis and 23 age- and sex-matched controls. The veins were assessed at the upper IJV (at C1-3 level) and the middle IJV (at C3-5 level). Grading of IJV compression/stenosis was determined bilaterally as follows: 0 = normal round or ovoid appearance; 1 = mild flattening; 2 = moderate flattening; and 3 = severe flattening or not visualized.
resultsThere was significantly more moderate or severe IJV compression/stenosis in the TMB patients at the left upper IJV level and the bilateral middle IJV level. Defining venous compression/stenosis scores ≥ 2 as a significant cerebral venous outflow impairment, TMB patients were found to have higher frequency of significant venous outflow impairment at the upper IJV level (56.5% vs. 8.7%, p = 0.0005) and the middle IJV level (69.6% vs. 21.7%, p=0.0011).
conclusionsTMB Patients with the absence of carotid stenosis had higher frequency and greater severity of IJV compression/stenosis which could impair cerebral venous outflow. Our results provide evidence supporting that the cerebral venous outflow abnormality is one of the etiologies of TMB.
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