ReviewAnnual review of genomics and human genetics2013
Growing up in the genomic era: implications of whole-genome sequencing for children, families, and pediatric practice.
Review in Annual review of genomics and human genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Precision Health Approaches in Primary Childhood Obesity Prevention: A Systematic Review of Tailored and Risk-Based Interventions.Pediatric obesity · 2026Pooled it
- Narrative review on ethical and psychological issues raised by genetic and genomic testing in pediatric oncology care.Journal of genetic counseling · 2025Review
- Psychological and ethical issues raised by genomic in paediatric care pathway, a qualitative analysis with parents and childhood cancer patients.European journal of human genetics : EJHG · 2024Article
- Genetics of liver disease in adults.Hepatology communications · 2024Review
- Parental Understanding of Their Child's Germline Genomic Testing: Intent of Disclosure to Their Child and Family.Journal of personalized medicine · 2023Article
- Genomic tools for health: Secondary findings as findings to be shared.Genetics in medicine : official journal of the American College of Medical Genetics · 2022Article
- FVC as an adaptive and accurate method for filtering variants from popular NGS analysis pipelines.Communications biology · 2022Article
- Young people's moral attitudes and motivations towards direct-to-consumer genetic testing for inherited risk of Alzheimer disease.European journal of medical genetics · 2021Article
- Next-Generation Sequencing in Newborn Screening: A Review of Current State.Frontiers in genetics · 2021Review
- Genome Diagnostics: Novel Strategies for Measuring Value.Journal of managed care & specialty pharmacy · 2019Article
- The experience of parents of children with rare diseases when communicating with healthcare professionals: towards an integrative theory of trust.Orphanet journal of rare diseases · 2019Article
- South Korea: in the midst of a privacy reform centered on data sharing.Human genetics · 2018Review
- Care and cost consequences of pediatric whole genome sequencing compared to chromosome microarray.European journal of human genetics : EJHG · 2017Article
- Predictive Genetic Testing of Children for Adult-Onset Conditions: Negotiating Requests with Parents.Journal of genetic counseling · 2017Article
- Preferences for the provision of whole genome sequencing services among young adults.PloS one · 2017Article
- Parents' experiences 12 years after newborn screening for genetic susceptibility to type 1 diabetes and their attitudes to whole-genome sequencing in newborns.Genetics in medicine : official journal of the American College of Medical Genetics · 2016Article
- "Is It Worth Knowing?" Focus Group Participants' Perceived Utility of Genomic Preconception Carrier Screening.Journal of genetic counseling · 2016Article
- "Not Tied Up Neatly with a Bow": Professionals' Challenging Cases in Informed Consent for Genomic Sequencing.Journal of genetic counseling · 2016Article
- Article
- Whole-genome sequencing in newborn screening? A statement on the continued importance of targeted approaches in newborn screening programmes.European journal of human genetics : EJHG · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Whole-genome sequencing (WGS) has advanced to a point where it is beginning to be integrated into pediatric practice. With little consensus on how to maximize the benefits of WGS for children, there is a growing need for focused efforts that connect researchers, clinicians, and families to chart a path forward. To illustrate relevant concerns, two contrasting applications of pediatric WGS are explored: clinical use with children who have undiagnosed conditions, and population-based screening. Specific challenges for health care services, policy development, and the well-being of children are discussed in light of current research. In the interest of ensuring evidence-based pediatric WGS, strategies are identified for advancing our understanding of what it means for children to grow up with WGS results guiding their health care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.