Trial reportPloS one2013
A paradigm of uphill running.
Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The effects of hormone changes over the menstrual cycle on elite athlete performance: meta-analysis and suggested standardised protocol.Reproduction & fertility · 2026Pooled it
- Effects of Combined Uphill-Downhill Sprinting Versus Resisted Sprinting Methods on Sprint Performance: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- The effects of uphill training on the maximal velocity and performance of middle-distance runners: a randomized controlled trial.Scientific reports · 2025Trial
- Biomechanical Responses to Level, Uphill, and Downhill Running Segments During an Outdoor Marathon.European journal of sport science · 2026Article
- Oxygen uptake on-kinetics during horizontal and uphill treadmill running in moderate- and severe-intensity domains.European journal of applied physiology · 2026Article
- Exploring Factors to Explain Interindividual Responses to Running Economy in Advanced Footwear Technology Shoes: A Randomised Crossover Laboratory Trial with an Explanatory Predictor Analysis.Sports medicine - open · 2026Article
- Modeling heart rate (HR) dynamics to reconstruct missing HR data in trail running.BMC sports science, medicine & rehabilitation · 2026Article
- Stress-Induced "Immediate" Lactate (iBLC) Response Differences in Pubertal and Young Adult Soccer Players.Sports (Basel, Switzerland) · 2025Article
- Mechanical Running Power and Energy Expenditure in Uphill and Downhill Running.Sports (Basel, Switzerland) · 2025Article
- Gait variability and fatigability during a simulated 10-km running race in trained runners.European journal of applied physiology · 2025Article
- A review of uphill and downhill running: biomechanics, physiology and modulating factors.Frontiers in bioengineering and biotechnology · 2025Review
- How Downhill and Uphill Running Interfere Posture and Muscle Activity: A Descriptive Laboratory Study.International journal of sports physical therapy · 2025Article
- Gait Variability at Different Walking Speeds.Journal of functional morphology and kinesiology · 2023Article
- Performance Level Affects Full Body Kinematics and Spatiotemporal Parameters in Trail Running-A Field Study.Sports (Basel, Switzerland) · 2023Article
- Carrying eggs uphill: are costs of reproduction stronger on steeper slopes?Biology letters · 2023Article
- A Classification Method for Workers' Physical Risk.Sensors (Basel, Switzerland) · 2023Article
- Increased oxygen uptake in well-trained runners during uphill high intensity running intervals: A randomized crossover testing.Frontiers in physiology · 2023Article
- Energy cost differences between marathon runners and soccer players: Constant versus shuttle running.Frontiers in physiology · 2023Article
- Contribution and effectiveness of ski and pole forces in selected roller skiing techniques on treadmill at moderate inclines.Frontiers in sports and active living · 2023Article
- The Energetic Costs of Uphill Locomotion in Trail Running: Physiological Consequences Due to Uphill Locomotion Pattern-A Feasibility Study.Life (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The biomechanical management of bioenergetics of runners when running uphill was investigated. Several metabolic and mechanical variables have been studied simultaneously to spread light on the locomotory strategy operated by humans for effective locomotion. The studied variables were: heart rate, heart rate variability, oxygen intake and blood lactate, metabolic cost, kinematics, ground reaction force and muscular activity. 18 high-level competitive male runners ran at 70% VO2max on different uphill slope conditions: 0%, 2% and 7%. Modifications were significant in almost all variables studied, and were more pronounced with increasing incline. Step frequency/length and ground reaction force are adjusted to cope with both the task of uphill progression and the available (limited) metabolic power. From 0% to 7% slope, step frequency and ground reaction force and metabolic cost increased concurrently by 4%, 12% and 53%, respectively (with a 4% step length decrease as well). It is hypothesised that this biomechanical management is allowed by an environment-body communication performed by means of specific muscular activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.