ArticlePloS one2013
Evidence of Multiple Disease Resistance (MDR) and implication of meta-analysis in marker assisted selection.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Genome-wide meta-QTL analyses provide novel insight into disease resistance repertoires in common bean.BMC genomics · 2022Pooled it
- Meta-QTLs for multiple disease resistance involving three rusts in common wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Pooled it
- Genetic dissection of maydis leaf blight resistance in maize through QTL mapping.Molecular biology reports · 2026Article
- Identification of gray leaf spot-resistant donor lines in tropical maize germplasm and their agronomic performance under artificial inoculation.Frontiers in plant science · 2025Article
- Current status of molecular rice breeding for durable and broad-spectrum resistance to major diseases and insect pests.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Review
- Insights into maydis leaf blight resistance in maize: a comprehensive genome-wide association study in sub-tropics of India.BMC genomics · 2024Article
- Genetic basis of resistance to southern corn leaf blight in the maize multi-parent population and diversity panel.Plant biotechnology journal · 2023Article
- Back to the wild: mining maize (Zea mays L.) disease resistance using advanced breeding tools.Molecular biology reports · 2022Article
- Unravelling consensus genomic regions conferring leaf rust resistance in wheat via meta-QTL analysis.The plant genome · 2022Article
- Meta-analysis reveals consensus genomic regions associated with multiple disease resistance in wheat (Molecular breeding : new strategies in plant improvement · 2022Article
- Genome-wide association studies in tropical maize germplasm reveal novel and known genomic regions for resistance to Northern corn leaf blight.Scientific reports · 2020Article
- Identification of Loci That Confer Resistance to Bacterial and Fungal Diseases of Maize.G3 (Bethesda, Md.) · 2020Article
- Validation and Characterization of Maize Multiple Disease Resistance QTL.G3 (Bethesda, Md.) · 2019Article
- A Statistical Procedure for Genome-Wide Detection of QTL Hotspots Using Public Databases with Application to Rice.G3 (Bethesda, Md.) · 2019Article
- Genetic insights into underground responses to Fusarium graminearum infection in wheat.Scientific reports · 2018Article
- Downy mildew disease promotes the colonization of romaine lettuce by Escherichia coli O157:H7 and Salmonella enterica.BMC microbiology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meta-analysis was performed for three major foliar diseases with the aim to find out the total number of QTL responsible for these diseases and depict some real QTL for molecular breeding and marker assisted selection (MAS) in maize. Furthermore, we confirmed our results with some major known disease resistance genes and most well-known gene family of nucleotide binding site (NBS) encoding genes. Our analysis revealed that disease resistance QTL were randomly distributed in maize genome, but were clustered at different regions of the chromosomes. Totally 389 QTL were observed for these three major diseases in diverse maize germplasm, out of which 63 QTL were controlling more than one disease revealing the presence of multiple disease resistance (MDR). 44 real-QTLs were observed based on 4 QTL as standard in a specific region of genome. We also confirmed the Ht1 and Ht2 genes within the region of real QTL and 14 NBS-encoding genes. On chromosome 8 two NBS genes in one QTL were observed and on chromosome 3, several cluster and maximum MDR QTL were observed indicating that the apparent clustering could be due to genes exhibiting pleiotropic effect. Significant relationship was observed between the number of disease QTL and total genes per chromosome based on the reference genome B73. Therefore, we concluded that disease resistance genes are abundant in maize genome and these results can unleash the phenomenon of MDR. Furthermore, these results could be very handy to focus on hot spot on different chromosome for fine mapping of disease resistance genes and MAS.
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