ArticleReproductive medicine and biology2013
Update in polycystic ovary syndrome: new criteria of diagnosis and treatment in Japan.
Article in Reproductive medicine and biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Association between periodontal disease and polycystic ovary syndrome: a systematic review.International journal of impotence research · 2017Pooled it
- Exenatide, Metformin, or Both for Prediabetes in PCOS: A Randomized, Open-label, Parallel-group Controlled Study.The Journal of clinical endocrinology and metabolism · 2021Trial
- A Generational Comparison of Physical and Laboratory Findings in Patients with Polyendocrine Metabolic Ovarian Syndrome in Japan.Journal of clinical medicine · 2026Article
- Global trends and health system impact on polycystic ovary syndrome: a comprehensive analysis of age-stratified females from 1990 to 2021.Frontiers in reproductive health · 2025Article
- Article
- Optimizing FSH Concentration Modulation in the Short-Acting GnRH-a Long Protocol for IVF/ICSI: A Retrospective Study.Advances in therapy · 2024Article
- Clinical Phenotypes of PCOS: a Cross-Sectional Study.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
- Study of Burden in Polycystic Ovary Syndrome at Global, Regional, and National Levels from 1990 to 2019.Healthcare (Basel, Switzerland) · 2023Article
- A novel orally active gonadotropin-releasing hormone antagonist, relugolix, is a potential substitute for injectable GnRH antagonists in controlled ovarian stimulation in assisted reproductive technology.Reproductive medicine and biology · 2022Article
- The Thickness and Density of the Ovarian Tunica Albuginea Increases with Age in Transgender Patients.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Is polycystic ovary syndrome appropriately diagnosed by obstetricians and gynaecologists across China: a nationwide survey.Journal of ovarian research · 2021Article
- Consecutive Low Doses of Streptozotocin Induce Polycystic Ovary Syndrome Features in Mice.International journal of molecular sciences · 2021Article
- Different anti-Műllerian hormone (AMH) levels respond to distinct ovarian stimulation methods in assisted reproductive technology (ART): Clues to better ART outcomes.Reproductive medicine and biology · 2019Article
- Animal models of polycystic ovary syndrome: A review of hormone-induced rodent models focused on hypothalamus-pituitary-ovary axis and neuropeptides.Reproductive medicine and biology · 2019Review
- Prevalence and Risk Factors of Elevated Liver Enzymes in Japanese Women With Polycystic Ovary Syndrome.Journal of clinical medicine research · 2018Article
- Weight reduction using a formula diet recovers menstruation in obese patients with an ovulatory disorder.Reproductive medicine and biology · 2017Article
- Clinical outcome of various metformin treatments for women with polycystic ovary syndrome.Reproductive medicine and biology · 2017Article
- Case-control study of metabolic syndrome and ovarian cancer in Chinese population.Nutrition & metabolism · 2017Article
- Polycystic ovary syndrome: early diagnosis and intervention are necessary for fertility preservation in young women with endometrial cancer under 35 years of age.Reproductive medicine and biology · 2017Article
- Association between serum gonadotropin level and insulin resistance-related parameters in Korean women with polycystic ovary syndrome.Obstetrics & gynecology science · 2016Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polycystic ovary syndrome (PCOS) is the most frequent endocrine disorder in women of reproductive age. In 2006 the Japanese Society of Obstetrics and Gynecology (JSOG) proposed new, revised diagnostic criteria that in the future could also be valued internationally. Based on the new diagnostic criteria, the JSOG has also proposed the revised treatment criteria in 2008. In PCOS obese patients desiring children, weight loss and exercise is recommended. Nonobese patients, or those obese women who do not ovulate after lifestyle changes, are submitted to ovulation-induction therapy with clomiphene citrate (CC). Obese CC-resistant patients who have impaired glucose tolerance or insulin resistance are treated with a combination of metformin and CC. If these treatments options are unsuccessful, ovulation induction with exogenous gonadotropin therapy or laparoscopic ovarian drilling (LOD) is recommended. A low-dose step-up regimen is recommended with careful monitoring in order to reduce the risk of ovarian hyperstimulation syndrome (OHSS) and multiple pregnancies. Alternatively, with LOD high successful pregnancy rates of around 60 % are expected with a low risk of multiple pregnancies. If ovulation induction is unsuccessful, IVF-ET treatment is indicated. In high OHSS-risk patients, systematic embryo freezing and subsequent frozen embryo transfer cycles are recommended. In nonobese, anovulatory PCOS patients not desiring children, pharmacological treatments such as Holmström, Kaufmann regimens or low-dose oral anticonceptives are used to induce regular withdrawal bleeding. These treatments are especially important for preventing endometrial hyperplasia and endometrial cancer. These new diagnostic and treatment criteria hopefully will contribute to an improved care of PCOS patients in Japan.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.