ArticleTransactions of the American Clinical and Climatological Association2013
Anemia in the elderly.
Article in Transactions of the American Clinical and Climatological Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Redefining the concept of erythrocyte senescence: is eryptosis fundamentally different from erythrocyte senescence.GeroScience · 2025Review
- Unmasking anemia in the elderly: A systematic review of prevalence, causes, and consequences.Journal of family medicine and primary care · 2025Review
- Blood transfusion in older surgical patients: the only option or is there a better approach?Aging clinical and experimental research · 2025Review
- The axis of tumor-associated macrophages, extracellular matrix proteins, and cancer-associated fibroblasts in oncogenesis.Cancer cell international · 2024Review
- A comprehensive analysis of age and 30-day complications following total shoulder arthroplasty: nonagenarians, octogenarians, and septuagenarians.JSES international · 2024Article
- Etiology of Anemia in Older Mexican Adults: The Role of Hepcidin, Vitamin A and Vitamin D.Nutrients · 2021Article
- Review
- Adverse Effects of Low-Dose Methotrexate in a Randomized Double-Blind Placebo-Controlled Trial: Adjudicated Hematologic and Skin Cancer Outcomes in the Cardiovascular Inflammation Reduction Trial.ACR open rheumatology · 2020Article
- To be red or white: lineage commitment and maintenance of the hematopoietic system by the "inner myeloid".Haematologica · 2019Review
- Anemia and blood transfusion in elderly trauma patients.The Journal of surgical research · 2018Article
- Gene therapy with the TRF1 telomere gene rescues decreased TRF1 levels with aging and prolongs mouse health span.Aging cell · 2017Article
- Blood transfusion in elderly patients with chronic anemia: a qualitative analysis of the general practitioners' attitudes.BMC family practice · 2017Article
- Prevalence of Anemia among Older Adults Residing in the Coastal and Andes Mountains in Ecuador: Results of the SABE Survey.Current gerontology and geriatrics research · 2017Article
- Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.Nature communications · 2016Article
- Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment.Frontiers in immunology · 2016Review
- Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias.PloS one · 2016Article
- INSULIN-LIKE GROWTH FACTOR-1 AND ANEMIA IN OLDER SUBJECTS: THE INCHIANTI STUDY.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2015Article
- Anemia in elderly hospitalized patients: prevalence and clinical impact.Internal and emergency medicine · 2015Observational
- Anemia in elderly residents of a long-term care institution.Hematology, transfusion and cell therapyArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the population ages, increasing attention has become focused on the prevalence of anemia in elderly individuals. Anemia occurs in more than 10% of individuals who are older than the age of 65 years, and it increases to more than 50% in individuals who are older than the age of 80 years. Although the anemia is typically mild and unlikely to result in symptoms, it is uniformly associated with increased morbidity and mortality as assessed in large cohort studies. Anemia is an independent predictor of these adverse outcomes both in healthy community-dwelling subjects and in patients with significant co-morbidities. Efforts to understand the pathophysiology of anemia in this population, especially the one third of patients with "unexplained" anemia, have focused on the potential contributions of inflammatory pathways, erythropoietin resistance, and changes in hematopoietic stem cells to the age-dependent decrease in red cell mass. We would argue that these pathways are closely interrelated and combine to lead to anemia in aging individuals. This brief review summarizes the current understanding of this entity and our studies aimed at further delineating its pathophysiology.
Indexed as
Identifiers
23874029PMC3715932W2097642366What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.