Evidence map›Paper›PMID 23873974›Full record

ArticleNeurology2013

The semiology of tilt-induced psychogenic pseudosyncope.

Martijn R Tannemaat, Julius van Niekerk, Robert H Reijntjes, Roland D Thijs, Richard Sutton, J Gert van Dijk

Abstract read
In one paragraph

Article in Neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 97 citations in OpenAlex.

  1. Difference in clinical characteristics between functional syncope and vasovagal syncope in children.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  2. Review
  3. Is it time to move beyond blood pressure and heart rate during head-up tilt testing?Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Article
  4. Article
  5. Definitive aetiology of unexplained syncope after cardiovascular autonomic tests in a tertiary syncope unit.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  6. Article
  7. A novel and practical method to add video monitoring to tilt table testing.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. [Young patient with recurrent unexplained syncope].Herzschrittmachertherapie & Elektrophysiologie · 2021
    Article
  13. Review
  14. Tilt testing remains a valuable asset.European heart journal · 2021
    Article
  15. Article
  16. Article
  17. Reflex syncope: Diagnosis and treatment.Journal of arrhythmia · 2017
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Martijn R TannemaatDepartment of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Amsterdam, the Netherlands.
Julius van Niekerk
Robert H Reijntjes
Roland D Thijs
Richard Sutton
J Gert van Dijk
Leiden University · NLNetherlands Institute for Neuroscience · NLRoyal Academy of Art · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo provide a detailed semiology to aid the clinical recognition of psychogenic pseudosyncope (PPS), which concerns episodes of apparent transient loss of consciousness (TLOC) that mimic syncope.

methodsWe analyzed all consecutive tilt-table tests from 2006 to 2012 showing proven PPS, i.e., apparent TLOC had occurred without EEG changes or a decrease in heart rate (HR) or blood pressure (BP). We analyzed baseline characteristics, video data, EEG, ECG, and continuous BP measurements on a 1-second time scale. Data were compared with those of 69 cases of tilt-induced vasovagal syncope (VVS).

resultsOf 800 tilt-table tests, 43 (5.4%) resulted in PPS. The majority (74%) were women. The median duration of apparent TLOC was longer in PPS (44 seconds) than in VVS (20 seconds, p < 0.05). During the event, the eyes were closed in 97% in PPS but in only 7% in VVS (p < 0.0001). A sudden head drop or moving down the tilt table was more common in PPS than in VVS (p < 0.01), but jerking movements occurred more frequently in VVS (p < 0.0001). In PPS, both HR and BP increased before and during apparent TLOC (p < 0.0001).

conclusionsPPS is clinically distinct from VVS and can be diagnosed accurately with tilt-table testing and simultaneous EEG monitoring. Compared with VVS, eye closure during the event, long periods of apparent TLOC, and high HR and BP are highly specific for PPS. Improved understanding of the semiology of PPS as a clinical entity is vital to ensure accurate diagnosis.

Indexed as

AdolescentAdultBlood PressureBlood Pressure DeterminationDiagnosis, DifferentialElectrocardiographyFemaleHeart RateHumansMaleMiddle AgedNetherlandsReproducibility of ResultsSensitivity and SpecificitySymptom AssessmentSyncope, Vasovagal

Identifiers

PMID23873974
PMCPMC3776458
OpenAlexW2149786680

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.