Evidence map›Paper›PMID 23873510›Full record

ArticleProteins2014

Assessment of CASP10 contact-assisted predictions.

Todd J Taylor, Hongjun Bai, Chin-Hsien Tai, Byungkook Lee

Abstract read
In one paragraph

Article in Proteins, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Todd J TaylorLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Hongjun Bai
Chin-Hsien Tai
Byungkook Lee

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
Structural BioinformaticsZIABC011233 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LEE, BYUNGKOOK · 2009 to 2015
$4.4M
MOLECULAR MODELING AND BIOINFORMATICSZ01BC008759 · NCI · BASIC SCIENCES · PI LEE, BYUNGKOOK · 1996 to 2007
$1.2M
Protein StructureZ01BC011000 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LEE, BYUNGKOOK · 2008 to 2008
$665k
Intramural NIH HHS Z01 BC008759Intramural NIH HHS Z01 BC011000NIGMS NIH HHS P41 GM103311PHS HHS NIGMS P41-GM103311
6 · The paper itself

Abstract

In CASP10, for the first time, contact-assisted structure predictions have been assessed. Sets of pairs of contacting residues from target structures were provided to predictors for a second round of prediction after the initial round in which they were given only sequences. The objective of the experiment was to measure model quality improvement resulting from the added contact information and thereby assess and help develop so-called hybrid prediction methods--methods where some experimentally determined distance constraints are used to augment de novo computational prediction methods. The results of the experiment were, overall, quite promising.

Indexed as

Models, MolecularProtein ConformationComputational BiologyModels, StatisticalProteinsSequence AlignmentProteinsCASP10contact assistedhybrid predictionprotein structure prediction

Identifiers

PMID23873510
PMCPMC6961783

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.