Evidence map›Paper›PMID 23873408›Full record

ReviewTopics in current chemistry2015

Sialic Acid Receptors of Viruses.

Mikhail Matrosovich, Georg Herrler, Hans Dieter Klenk

Open access · bronzeAbstract readReview
In one paragraph

Review in Topics in current chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed
21.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 277 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Paramyxovirus infection driven by heteromultivalent sialoglycotope binding.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. FUT1- and GAL3ST2-mediated cellular glycan remodeling broadly restricts sialic acid-dependent viral infections.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  13. Article
  14. Article
  15. Host Glycan-Lectin Interplay in SARS-CoV-2 Infection.International journal of molecular sciences · 2026
    Review
  16. Review
  17. Review
  18. Journal of virology · 2025
    Article
  19. Review
  20. Article

120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mikhail MatrosovichInstitut für Virologie, Philipps-Universität, Hans-Meerwein-Str. 2, 35043, Marburg, Germany.
Georg Herrler
Hans Dieter Klenk
Philipps University of Marburg · DEUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

Wellcome TrustWellcome Trust WT085572MF
6 · The paper itself

Abstract

Sialic acid linked to glycoproteins and gangliosides is used by many viruses as a receptor for cell entry. These viruses include important human and animal pathogens, such as influenza, parainfluenza, mumps, corona, noro, rota, and DNA tumor viruses. Attachment to sialic acid is mediated by receptor binding proteins that are constituents of viral envelopes or exposed at the surface of non-enveloped viruses. Some of these viruses are also equipped with a neuraminidase or a sialyl-O-acetyl-esterase. These receptor-destroying enzymes promote virus release from infected cells and neutralize sialic acid-containing soluble proteins interfering with cell surface binding of the virus. Variations in the receptor specificity are important determinants for host range, tissue tropism, pathogenicity, and transmissibility of these viruses.

Indexed as

AcetylesteraseAnimalsCell MembraneEukaryotic CellsHumansNeuraminidaseProtein BindingReceptors, Cell SurfaceReceptors, VirusSialic AcidsSpecies SpecificityViral ProteinsViral TropismVirusesVirus InternalizationAcetylesteraseNeuraminidaseReceptors, Cell SurfaceReceptors, Virussialate O-acetylesterasesialic acid receptorSialic AcidsViral Proteins

Identifiers

PMID23873408
PMCPMC7120183
OpenAlexW137951132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.