ArticleMolecules (Basel, Switzerland)2013
Preliminary phytochemical screening and antibacterial properties of crude stem bark extracts and fractions of Parkia biglobosa (Jacq.).
Article in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- GenusInternational journal of molecular sciences · 2021Pooled it
- Gastroprotective, Antioxidant, Anti-Inflammatory, and Toxicological Evaluation of Stem Bark Extracts ofPharmaceuticals (Basel, Switzerland) · 2025Article
- Contemporary Insights into the Biological Mechanisms ofInternational journal of environmental research and public health · 2024Review
- Production of Biodiesel from NonedibleTheScientificWorldJournal · 2023Article
- Validation of Antidiabetic and Antihyperlipidemic Effects of 80% Methanolic Extract of theEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Proconvulsant effects ofHeliyon · 2020Article
- Antidepressant and anxiolytic activity of Lavandula officinalis aerial parts hydroalcoholic extract in scopolamine-treated rats.Pharmaceutical biology · 2017Article
- Attitudes and use of medicinal plants during pregnancy among women at health care centers in three regions of Mali, West-Africa.Journal of ethnobiology and ethnomedicine · 2015Article
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Authors and funding
6 authors.
Funding
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Abstract
A methanolic crude extract of Parkia biglobosa was prepared and later partitioned in succession with different solvents of increasing polarity ranging from n-hexane, chloroform and ethyl acetate to butanol. Phytochemical screening of the extract revealed the presence of alkaloids, tannins, saponins, flavonoids, steroids, glycoside and sugars. The inhibition zones exhibited by the extract against the tested bacteria ranged between 14 ± 0.00 mm (against Escherichia coli) and 28 ± 0.71 mm (against Pseudomonas aeruginosa). The MIC of the methanolic extract of P. biglobosa against isolates ranged between 0.63 mg/mL and 5 mg/mL, while the MIC values exhibited by the n-hexane and aqueous fractions ranged between 0.63 mg/mL and 10 mg/mL. Overall the extract and fractions of P. biglobosa used in this work were found to possess antimicrobial properties which compared favourably with those of streptomycin. These observations make this plant a potential source of bioactive compounds that can be used in management of bacterial infections. The use of this plant as herbal medicaments in African countries and the reports on the toxicity of the plant further show that the plant is non-toxic to humans.
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