Evidence map›Paper›PMID 23872831›Full record

ArticleClinical pharmacology and therapeutics2013

CYP2D6 genotype and tamoxifen activity: understanding interstudy variability in methodological quality.

M J Ratain, Y Nakamura, N J Cox

Abstract readComment
In one paragraph

Article in Clinical pharmacology and therapeutics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Defining Clinical Utility of Germline Indicators of Toxicity Risk: A Perspective.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Effects ofBreast cancer (Dove Medical Press) · 2017
    Article
  12. Article
  13. Article
  14. Endocrine resistance in breast cancer--An overview and update.Molecular and cellular endocrinology · 2015
    Review
  15. Review
  16. Review
  17. Addressing phenoconversion: the Achilles' heel of personalized medicine.British journal of clinical pharmacology · 2015
    Review
  18. Observational
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

M J RatainDepartment of Medicine, The University of Chicago, Chicago, Illinois, USA. mratain@medicine.bsd.uchicago.edu
Y Nakamura
N J Cox

Funding

Whole GenomeU01GM061393 · NIGMS · UNIVERSITY OF CHICAGO · PI COX, NANCY J, DOLAN, MARY EILEEN · 2000 to 2014
$39.0M
NIGMS NIH HHS U01 GM061393NIGMS NIH HHS U01 GM61393
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Breast NeoplasmsCytochrome P-450 CYP2D6Estrogen AntagonistsFemaleHumansTamoxifenCytochrome P-450 CYP2D6Estrogen AntagonistsTamoxifen

Identifiers

PMID23872831
PMCPMC3782290

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.