Evidence map›Paper›PMID 23872491›Full record

ReviewViruses2013

Nuclear imprisonment: viral strategies to arrest host mRNA nuclear export.

Sharon K Kuss, Miguel A Mata, Liang Zhang, Beatriz M A Fontoura

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Virus Infection and mRNA Nuclear Export.International journal of molecular sciences · 2023
    Review
  8. Review
  9. Article
  10. Reovirus μ2 Protein Impairs Translation to Reduce U5 snRNP Protein Levels.International journal of molecular sciences · 2022
    Article
  11. Review
  12. The global succinylation of SARS-CoV-2-infected host cells reveals drug targets.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sharon K KussDepartment of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Sharon.Kuss@utsouthwestern.edu
Miguel A Mata
Liang Zhang
Beatriz M A Fontoura
The University of Texas Southwestern Medical Center · US

Funding

Novel Inhibitors of Viral ReplicationR01AI089539 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI FONTOURA, BEATRIZ MA, ROTH, MICHAEL G · 2010 to 2014
$2.0M
Using Chemical Biology to Interfere with the Influenza Virus Life CycleR01AI079110 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI FONTOURA, BEATRIZ MA, ROTH, MICHAEL G · 2010 to 2014
$2.0M
Infectious Diseases Training ProgramT32AI070116 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI PERL, TRISH M. · 2007 to 2017
$1.1M
NIAID NIH HHS R01 AI079110NIAID NIH HHS R01 AI089539NIAID NIH HHS R01AI089539NIAID NIH HHS T32 AI070116NIAID NIH HHS T32AI070116-06NIGMS NIH HHS R01GM07159
6 · The paper itself

Abstract

Viruses possess many strategies to impair host cellular responses to infection. Nuclear export of host messenger RNAs (mRNA) that encode antiviral factors is critical for antiviral protein production and control of viral infections. Several viruses have evolved sophisticated strategies to inhibit nuclear export of host mRNAs, including targeting mRNA export factors and nucleoporins to compromise their roles in nucleo-cytoplasmic trafficking of cellular mRNA. Here, we present a review of research focused on suppression of host mRNA nuclear export by viruses, including influenza A virus and vesicular stomatitis virus, and the impact of this viral suppression on host antiviral responses.

Indexed as

Active Transport, Cell NucleusHost-Pathogen InteractionsImmune EvasionInfluenza A virusRNA, MessengerVesiculovirusViral ProteinsRNA, MessengerViral Proteins

Identifiers

PMID23872491
PMCPMC3738964
OpenAlexW1982198730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.