Evidence map›Paper›PMID 23872040›Full record

ArticleUltramicroscopy2013

Simulating realistic imaging conditions for in situ liquid microscopy.

David A Welch, Roland Faller, James E Evans, Nigel D Browning

Abstract read
In one paragraph

Article in Ultramicroscopy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. High-Resolution Imaging and Spectroscopy at High Pressure: A Novel Liquid Cell for the Transmission Electron Microscope.Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David A WelchDepartment of Chemical Engineering and Materials Science, University of California, Davis, CA, USA. Electronic address: dawelch@ucdavis.edu.
Roland Faller
James E Evans
Nigel D Browning

Funding

A Dynamic TEM to Observe Biological Processes on the Nanosecond and Nanometer ScaS10RR025032 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BROWNING, NIGEL DAVID · 2009 to 2009
$2.0M
Real-time imaging of dynamic biological processes at nanometer spatial resolutionRC1GM091755 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI EVANS, JAMES E · 2009 to 2010
$999k
NCRR NIH HHS RR025032-01NCRR NIH HHS S10 RR025032NIGMS NIH HHS 5RC1GM091755NIGMS NIH HHS RC1 GM091755
6 · The paper itself

Abstract

In situ transmission electron microscopy enables the imaging of biological cells, macromolecular protein complexes, nanoparticles, and other systems in a near-native environment. In order to improve interpretation of image contrast features and also predict ideal imaging conditions ahead of time, new virtual electron microscopic techniques are needed. A technique for virtual fluid-stage high-angle annular dark-field scanning transmission electron microscopy with the multislice method is presented that enables the virtual imaging of model fluid-stage systems composed of millions of atoms. The virtual technique is exemplified by simulating images of PbS nanoparticles under different imaging conditions and the results agree with previous experimental findings. General insight is obtained on the influence of the effects of fluid path length, membrane thickness, nanoparticle position, defocus and other microscope parameters on attainable image quality.

Indexed as

Atomistic modelImage simulationIn situ microscopyNanoparticle growth

Identifiers

PMID23872040
PMCPMC3808501

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.