SynthesisBMJ clinical evidence2012
Chronic suppurative otitis media.
Synthesis in BMJ clinical evidence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 6 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Antibiotics versus topical antiseptics for chronic suppurative otitis media.The Cochrane database of systematic reviews · 2025Pooled it
- Topical antiseptics for chronic suppurative otitis media.The Cochrane database of systematic reviews · 2025Pooled it
- Topical antibiotics with steroids for chronic suppurative otitis media.The Cochrane database of systematic reviews · 2025Pooled it
- Topical antibiotics with steroids for chronic suppurative otitis media.The Cochrane database of systematic reviews · 2020Pooled it
- Antibiotics versus topical antiseptics for chronic suppurative otitis media.The Cochrane database of systematic reviews · 2020Pooled it
- Topical antiseptics for chronic suppurative otitis media.The Cochrane database of systematic reviews · 2020Pooled it
- Mapping the Regenerative Pattern in the Human Tympanic Membrane.Audiology & neuro-otology · 2026Article
- Article
- A novel instrument for assessing health-related quality of life in French patients: translation and multi-centre validation of the Zurich chronic middle ear inventory (ZCMEI-21-Fr).European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Management Strategies for Chronic Suppurative Otitis Media and Why They Fail.Journal of the Association for Research in Otolaryngology : JARO · 2025Review
- Preliminary results of a new endoscopic underlay cartilage tympanoplasty with lateral malleolar flap.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Patterns of Ear Morbidities Among Pediatric Age Group: A Tertiary Care Hospital-Based Study.Cureus · 2025Article
- Article
- Article
- Comparison of Lateral Semicircular Canal Dysfunction in Chronic Otitis Media Patients using Air Caloric Test and Video Head Impulse Test.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Analysis of the Clinical Symptom Improvement and Recurrence Rate in Chronic Suppurative Otitis Media Patients Treated with Combination Therapy: Combination of Ofloxacin and Dexamethasone.Risk management and healthcare policy · 2025Article
- Chronic suppurative otitis media: disrupted host-microbial interactions and immune dysregulation.Frontiers in immunology · 2025Review
- Clinical and Pathological Characteristics of Chronic Otomastoiditis: A Retrospective Analysis of Risk Factors, Outcomes, and Antibiotic Resistance Patterns.Healthcare (Basel, Switzerland) · 2024Article
- Article
- Audiometric Outcomes in Chronic Otitis Media with Mastoid Involvement: A Five-Year Clinical Overview.Diagnostics (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionChronic suppurative otitis media (CSOM) is a common cause of hearing impairment and disability. Occasionally it can lead to fatal intracranial infections and acute mastoiditis, especially in developing countries. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of treatments for chronic suppurative otitis media in adults and in children? What are the effects of treatments for cholesteatoma in adults and in children? We searched: Medline, Embase, The Cochrane Library, and other important databases up to May 2010 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
resultsWe found 51 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
conclusionsIn this systematic review, we present information relating to the effectiveness and safety of the following interventions: topical ear cleansing, surgery for cholesteatoma, systemic antibiotics, topical antibiotics, topical antibiotics plus topical corticosteroids, topical antiseptics, topical corticosteroids, tympanoplasty (with or without mastoidectomy).
Indexed as
Identifiers
23870746PMC3412293W1515577635What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.