Evidence map›Paper›PMID 23870137›Full record

ReviewTrends in genetics : TIG2013

Balancing chromatin remodeling and histone modifications in transcription.

Emily Petty, Lorraine Pillus

Abstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 106 citations in OpenAlex.

  1. Review
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  3. Article
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  7. Recipes and ingredients for deep learning models of 3D genome folding.Current opinion in genetics & development · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Epigenetics as a target to mitigate excess stroke risk in people of African ancestry: A scoping review.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2024
    Article
  12. Article
  13. Review
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  17. Insight into the Epigenetics of Kaposi's Sarcoma-Associated Herpesvirus.International journal of molecular sciences · 2023
    Review
  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Emily PettyUniversity of California, San Diego, Division of Biological Sciences, Molecular Biology, UCSD Moores Cancer Center, 9500 Gilman Drive, La Jolla, CA 92093-0347, USA.
Lorraine Pillus
University of California, San Diego · US

Funding

SAS GENE FUNCTIONS AND CHROMATIN AND SILENCINGR01GM056469 · NIGMS · UNIVERSITY OF COLORADO AT BOULDER · PI PILLUS, LORRAINE · 1997 to 2007
$1.6M
Chromatin Regulation by Deacetylation and SUMO-Targeted Ubiquitin LigationR01GM090177 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PILLUS, LORRAINE · 2009 to 2012
$1.3M
NIGMS NIH HHS GM056469NIGMS NIH HHS GM090177NIGMS NIH HHS R01 GM056469NIGMS NIH HHS R01 GM090177
6 · The paper itself

Abstract

Chromatin remodelers use the energy of ATP hydrolysis to reposition or evict nucleosomes or to replace canonical histones with histone variants. By regulating nucleosome dynamics, remodelers gate access to the underlying DNA for replication, repair, and transcription. Nucleosomes are subject to extensive post-translational modifications that can recruit regulatory proteins or alter the local chromatin structure. Just as extensive crosstalk has been observed between different histone post-translational modifications, there is growing evidence for both coordinated and antagonistic functional relations between nucleosome remodeling and modifying machineries. Defining the combined functions of the complexes that alter nucleosome interactions, position, and stability is key to understanding processes that require access to DNA, particularly with growing appreciation of their contributions to human health and disease. Here, we highlight recent advances in the interactions between histone modifications and the imitation-switch (ISWI) and chromodomain helicase DNA-binding protein 1 (CHD1) chromatin remodelers from studies in budding yeast, fission yeast, flies, and mammalian cells, with a focus on yeast.

Indexed as

Adenosine TriphosphatasesAnimalsChromatin Assembly and DisassemblyDipteraDNA-Binding ProteinsHistonesMammalsProtein Processing, Post-TranslationalSaccharomyces cerevisiaeSchizosaccharomycesTranscription FactorsAdenosine TriphosphatasesDNA-Binding ProteinsHistonesISWI proteinTranscription FactorsChd1chromatinhistone modificationISWInucleosomeyeast

Identifiers

PMID23870137
PMCPMC4408995
OpenAlexW2157149216

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.