Evidence map›Paper›PMID 23870116›Full record

ArticleCell2013

Glia keep synapse distribution under wraps.

Laura E Clarke, Ben A Barres

Abstract readComment
In one paragraph

Article in Cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Defective Astrocyte Maturation Drives Cerebellar Neuroinflammation and Degeneration.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  2. Review
  3. Single-Cell Transcriptomics Supports a Role ofInternational journal of molecular sciences · 2021
    Review
  4. Macroglial diversity: white and grey areas and relevance to remyelination.Cellular and molecular life sciences : CMLS · 2021
    Review
  5. Review
  6. Glial evolution as a determinant of human behavior and its disorders.Annals of the New York Academy of Sciences · 2020
    Review
  7. Review
  8. Progress in iPSC-Based Modeling of Psychiatric Disorders.International journal of molecular sciences · 2019
    Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Laura E ClarkeDepartment of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA. lclarke2@stanford.edu
Ben A Barres

Funding

Testing a new hypothesis for CNS synaptic senescenceR01AG048814 · NIA · STANFORD UNIVERSITY · PI SHATZ, CARLA J · 2014 to 2017
$1.3M
NIA NIH HHS R01 AG048814
6 · The paper itself

Abstract

The wiring of the nervous system requires that axons navigate to the correct targets and maintain their correct positions during developmental growth. In this issue, Shao et al. (2013) now reveal a crucial new role for glia in preserving correct synaptic connectivity during developmental growth.

Indexed as

SynapsesAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsNeurogliaReceptors, Fibroblast Growth FactorSodium-Phosphate Cotransporter Proteins, Type ICaenorhabditis elegans ProteinsCIMA-1 protein, C elegansEGL-15 protein, C elegansReceptors, Fibroblast Growth FactorSodium-Phosphate Cotransporter Proteins, Type I

Identifiers

PMID23870116
PMCPMC4438748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.