ArticleJournal of pharmaceutical and biomedical analysis2014
Orthogonal analytical methods for botanical standardization: determination of green tea catechins by qNMR and LC-MS/MS.
Article in Journal of pharmaceutical and biomedical analysis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 54 citations in OpenAlex.
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- The Importance of Reference Materials and Method Validation for Advancing Research on the Health Effects of Dietary Supplements and Other Natural Products.Frontiers in nutrition · 2021Review
- Proanthocyanidin Dimers and Trimers fromJournal of natural products · 2019Article
- Selection and characterization of botanical natural products for research studies: a NaPDI center recommended approach.Natural product reports · 2019Review
- Dynamics of the isoflavone metabolome of traditional preparations of Trifolium pratense L.Journal of ethnopharmacology · 2019Article
- Simultaneous Quantification of Ellagitannins and Related Polyphenols inMolecules (Basel, Switzerland) · 2018Article
- Effect of interaction of epigallocatechin gallate and flavonols on color alteration of simulative green tea infusion after thermal treatment.Journal of food science and technology · 2017Article
- Evolution of Quantitative Measures in NMR: Quantum Mechanical qHNMR Advances Chemical Standardization of a Red Clover (Trifolium pratense) Extract.Journal of natural products · 2017Article
- Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa.Journal of natural products · 2016Article
- Digital NMR profiles as building blocks: assembling ¹H fingerprints of steviol glycosides.Journal of natural products · 2015Article
- A galloylated dimeric proanthocyanidin from grape seed exhibits dentin biomodification potential.Fitoterapia · 2015Article
- Effects of tea polyphenols on proliferation and apoptosis of cadmium-transformed cells.International journal of clinical and experimental medicine · 2015Article
- Importance of purity evaluation and the potential of quantitative ¹H NMR as a purity assay.Journal of medicinal chemistry · 2014Review
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
The development of analytical methods for parallel characterization of multiple phytoconstituents is essential to advance the quality control of herbal products. While chemical standardization is commonly carried out by targeted analysis using gas or liquid chromatography-based methods, more universal approaches based on quantitative (1)H NMR (qHNMR) measurements are being used increasingly in the multi-targeted assessment of these complex mixtures. The present study describes the development of a 1D qHNMR-based method for simultaneous identification and quantification of green tea constituents. This approach utilizes computer-assisted (1)H iterative Full Spin Analysis (HiFSA) and enables rapid profiling of seven catechins in commercial green tea extracts. The qHNMR results were cross-validated against quantitative profiles obtained with an orthogonal LC-MS/MS method. The relative strengths and weaknesses of both approaches are discussed, with special emphasis on the role of identical reference standards in qualitative and quantitative analyses.
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