Evidence map›Paper›PMID 23869522›Full record

ArticleOrganic letters2013

Dendrimers terminated with dichlorotriazine groups provide a route to compositional diversity.

Subrata Patra, Brittany Kozura, Adela Y-T Huang, Alan E Enciso, Xiankai Sun, Jer-Tsong Hsieh, Chai-Lin Kao, Hui-Ting Chen, Eric E Simanek

Abstract read
In one paragraph

Article in Organic letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Solid-Phase Synthesis of Well-Defined Defect Lysine Dendrimers.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  2. Article
  3. Two Decades of Triazine Dendrimers.Molecules (Basel, Switzerland) · 2021
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Subrata PatraDepartment of Chemistry, Texas Christian University, Fort Worth, Texas 76129, USA.
Brittany Kozura
Adela Y-T Huang
Alan E Enciso
Xiankai Sun
Jer-Tsong Hsieh
Chai-Lin Kao
Hui-Ting Chen
Eric E Simanek

Funding

Targeting aggressive prostate cancer with novel theranostic nanomedicineR01CA159144 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI HSIEH, JER-TSONG · 2011 to 2015
$1.6M
NCI NIH HHS 1R01CA 159144-01NCI NIH HHS R01 CA159144
6 · The paper itself

Abstract

Triazine dendrimers terminated with either four or eight dichlorotriazines can be prepared in high yields by reacting an amine-terminated dendrimer with cyanuric chloride. These materials exist as white powders and are stable to storage at room temperature. Sequential nucleophilic aromatic substitution with two different amine nucleophiles yields compounds that display the desired compositional diversity. Reaction conditions for the substitution were developed using a model dichlorotriazine with amine nucleophiles at -20, 0, and 25 °C. Selective substitution is favored at lower temperatures and with more nucleophilic amine groups.

Indexed as

AminesDendrimersMolecular StructureTriazinesAminescyanuric chlorideDendrimersTriazines

Identifiers

PMID23869522
PMCPMC4091816

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.