ArticleJournal of human reproductive sciences2013
Ovulation and rate of implantation following unilateral ovariectomy in mice.
Article in Journal of human reproductive sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Follicular development and the expression of BAX and vascular endothelial growth factor in transplanted ovaries in uni- and bilateral ovariectomized mice: An experimental study.International journal of reproductive biomedicine · 2021Article
- Unilateral salpingectomy in Sprague Dawley rats and its effect on litter size.Journal of the South African Veterinary Association · 2021Article
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1 author at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesRemoval of an ovary of any side of the body is called the unilateral ovariectomy (ULO). ULO models are used to analyze the existence of functional and physiological asymmetries between the ovaries, including the ovum implantation. MATERIALS AND
methodsULO was done in mice without any specification on their stages of the estrous cycle. The animals were mated between 3(rd) and 15(th) day after ULO to observe the consequence of ULO on ovulation and ovum implantation.
resultsOvulation and number of implantation were decreased in proportion to single contralateral ovary if the animals were mated within 36 hrs of ULO. It resulted in increased weight of contralateral ovary due to hypertrophy, and also in compensatory ovulation, formation of corpus luteum (CL) that reached a peak after 14(th) and 15(th) day of ULO (sacrificed on 5(th) day of pregnancy i.e., 19(th) and 20(th) day of ULO) compared to animals undergone sham-surgery. Numbers of implantations were also increased progressively on the contralateral ovarian side and get to a peak after similar days of compensation. DISCUSSION AND
conclusionFollowing ULO, the remaining ovary started to compensate within 5(th) to 6(th) day of ULO even during pregnancy. Ovarian histology also showed increased formation of CL which is a marker of rate of ovulation.
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