ReviewClinical journal of the American Society of Nephrology : CJASN2013
Beyond the futility argument: the fair process approach and time-limited trials for managing dialysis conflict.
Review in Clinical journal of the American Society of Nephrology : CJASN, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Futility in healthcare among Mexican female patients with breast cancer in advanced stage: The patient perspective.PloS one · 2025Article
- Muslim Jurisprudence on Withdrawing Treatment from Incurable Patients: A Directed Content Analysis of the Papers of the Islamic Fiqh Council of the Muslim World League.Journal of religion and health · 2024Article
- Defining the Time-limited Trial for Patients with Critical Illness: An Official American Thoracic Society Workshop Report.Annals of the American Thoracic Society · 2024Article
- Portuguese Advance Directives-a twist against futility? A cross sectional study.Sao Paulo medical journal = Revista paulista de medicina · 2024Article
- Transitions of dialysis status and outcomes after the unplanned first dialysis: a nationwide population-based cohort study.Scientific reports · 2023Article
- Healthcare professional education in shared decision making in the context of chronic kidney disease: a scoping review.BMC nephrology · 2023Article
- Frequency and Severity of Moral Distress in Nephrology Fellows: A National Survey.American journal of nephrology · 2021Article
- The current and future landscape of dialysis.Nature reviews. Nephrology · 2020Review
- Ethical challenges in nephrology: a call for action.Nature reviews. Nephrology · 2020Review
- Time-Limited Trials Among Critically Ill Patients With Advanced Medical Illnesses to Reduce Nonbeneficial Intensive Care Unit Treatments: Protocol for a Multicenter Quality Improvement Study.JMIR research protocols · 2019Article
- Explaining the Process of Determining Futility Increases Lay Public Acceptance.Annals of the American Thoracic Society · 2019Article
- Futile Treatment-A Review.Journal of bioethical inquiry · 2017Review
- Management dilemmas in pediatric nephrology: time-limited trials of dialysis therapy.Pediatric nephrology (Berlin, Germany) · 2017Article
- The Full Spectrum of Clinical Ethical Issues in Kidney Failure. Findings of a Systematic Qualitative Review.PloS one · 2016Article
- Pro and con arguments in using alternative dialysis regimens in the frail and elderly patients.International urology and nephrology · 2015Review
- Using time-limited trials to improve surgical care for frail older adults.Annals of surgery · 2015Article
- New concepts in palliative care in the intensive care unit.Revista Brasileira de terapia intensivaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Futility is an ancient concept arising from Greek mythology that was resurrected for its medical application in the 1980s with the proliferation of many lifesaving technologies, including dialysis and renal transplantation. By that time, the domineering medical paternalism that characterized the pre-1960s physician-patient relationship morphed into assertive patient autonomy, and some patients began to claim the right to demand aggressive, high-technology interventions, despite physician disapproval. To counter this power struggle, the establishment of a precise definition of futility offered hope for a futility policy that would allow physicians to justify withholding or withdrawing treatment, despite patient and family objections. This article reviews the various attempts made to define medical futility and describes their limited applicability to dialysis. When futility concerns arise, physicians should recognize the opportunity to address conflict, using best practice communication skills. Physicians would also benefit from understanding the ethical principles of respect for patient autonomy, beneficence, nonmaleficence, justice, and professional integrity that underlie medical decision-making. Also reviewed is the use of a fair process approach or time-limited trial when conflict resolution cannot be achieved. These topics are addressed in the Renal Physician Association's clinical practice guideline Shared Decision-Making in the Appropriate Initiation and Withdrawal from Dialysis, with which nephrologists should be well versed. A case presentation of intractable calciphylaxis in a new dialysis patient illustrates the pitfalls of physicians not fully appreciating the ethics of medical decision-making and failing to use effective conflict management approaches in the clinical practice guideline.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.