Evidence map›Paper›PMID 23868376›Full record

ArticleBiochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

Protein structure in context: the molecular landscape of angiogenesis.

Elise A Span, David S Goodsell, Ramani Ramchandran, Margaret A Franzen, Tim Herman, Daniel S Sem

Abstract read
In one paragraph

Article in Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Protein Neighbors and Proximity Proteomics.Molecular & cellular proteomics : MCP · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elise A SpanDepartment of Pharmaceutical Sciences, Concordia University Wisconsin, Mequon, WI 53097, USA
David S Goodsell
Ramani Ramchandran
Margaret A Franzen
Tim Herman
Daniel S Sem

Funding

Targeting DUSP-5 to Treat Vascular AnomaliesR01HL112639 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI RAMCHANDRAN, RAMANI · 2012 to 2016
$2.6M
Snrk-1 and Dusp-5 co-ordinately regulate vascular development in vertebratesR01HL102745 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI RAMCHANDRAN, RAMANI · 2011 to 2014
$1.5M
600 MHz Nuclear Magnetic Resonance SpectrometerS10RR019012 · NCRR · MARQUETTE UNIVERSITY · PI SEM, DANIEL S · 2005 to 2005
$500k
NCRR NIH HHS S10 RR019012NHLBI NIH HHS HL102745-01A1NHLBI NIH HHS HL112639-01NHLBI NIH HHS R01 HL102745NHLBI NIH HHS R01 HL112639
6 · The paper itself

Abstract

A team of students, educators, and researchers has developed new materials to teach cell signaling within its cellular context. Two nontraditional modalities are employed: physical models, to explore the atomic details of several of the proteins in the angiogenesis signaling cascade, and illustrations of the proteins in their cellular environment, to give an intuitive understanding of the cellular context of the pathway. The experiences of the team underscore the use of these types of materials as an effective mode for fostering students' understanding of the molecular world and the scientific method used to define it.

Indexed as

Signal TransductionAngiogenesis Inducing AgentsCurriculumHumansModels, TheoreticalMolecular BiologyMolecular StructureProteinsStudentsAngiogenesis Inducing AgentsProteinsangiogenesisprotein structureVEGF signalingvisual learning

Identifiers

PMID23868376
PMCPMC4074543

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.