SynthesisAJNR. American journal of neuroradiology2014
Vertebral augmentation in patients with multiple myeloma: a pooled analysis of published case series.
Synthesis in AJNR. American journal of neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Vertebral Augmentation Involving Vertebroplasty or Kyphoplasty for Cancer-Related Vertebral Compression Fractures: A Systematic Review.Ontario health technology assessment series · 2016Pooled it
- Long-term outcome following vertebroplasty or bone cementoplasty in multiple myeloma patients.Neuroradiology · 2025Article
- Practice variations in indication, timing and outcome of Multiple Myeloma patients undergoing surgery for vertebral lesions - results from the European M2Spine study group.Journal of neuro-oncology · 2025Article
- Review
- Treatment approaches for multiple Myeloma vertebral column lesions - Results from an international survey distributed to the AO spine knowledge forum tumor.Brain & spine · 2025Article
- Percutaneous vertebroplasty/kyphoplasty contributes to the improved outcome in patients with newly diagnosed multiple myeloma: A single center cohort study.Journal of bone oncology · 2024Article
- The Role of Vertebral Augmentation Procedures in the Management of Multiple Myeloma.Clinical hematology international · 2024Review
- Risk-benefit ratio of percutaneous kyphoplasty and percutaneous vertebroplasty in patients with newly diagnosed multiple myeloma with vertebral fracture: a single-center retrospective study.Annals of hematology · 2023Review
- Pain in the Cancer Survivor.Cancer treatment and research · 2021Article
- Evidence-based supportive care in multiple myeloma.Journal of community hospital internal medicine perspectives · 2020Review
- Multiple Myeloma Associated Bone Disease.Cancers · 2020Review
- VERTEBROPLASTY IN THE TREATMENT OF VERTEBRAL FRACTURES CAUSED BY PLASMACYTOMA.Acta clinica Croatica · 2019Article
- Bone marrow washout for multilevel vertebroplasty in multiple myeloma spinal involvement. Technical note.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019Article
- The role of cement augmentation with percutaneous vertebroplasty and balloon kyphoplasty for the treatment of vertebral compression fractures in multiple myeloma: a consensus statement from the International Myeloma Working Group (IMWG).Blood cancer journal · 2019Article
- Image-Guided Bone Consolidation in Oncology.Seminars in interventional radiology · 2018Review
- Balloon kyphoplasty and additional anterior odontoid screw fixation for treatment of unstable osteolytic lesions of the vertebral body C2: a case series.BMC musculoskeletal disorders · 2018Article
- Comparative analysis of the surgical treatment results for multiple myeloma bone disease of the spine and the long bone/soft tissue.Oncology letters · 2018Article
- Retained needle after cement injection during vertebral augmentation and its management strategy.BMJ case reports · 2016Article
- Effectiveness of percutaneous vertebroplasty in patients with multiple myeloma having vertebral pain.Diagnostic and interventional radiology (Ankara, Turkey)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeStudies examining the efficacy of vertebroplasty and kyphoplasty in patients with vertebral fractures from multiple myeloma are limited. We sought to perform a systematic review of published case studies examining changes in pain, disability, and analgesic drug use in patients with multiple myeloma who have undergone vertebral augmentation. MATERIALS AND
methodsWe performed a pooled analysis of published case series of vertebral augmentation in patients with multiple myeloma. Twenty-three studies (9 kyphoplasty, 12 vertebroplasty, and 2 of both) with data on 923 patients were identified from a PubMed search. Quantitative outcome data included the Visual Analog Scale, the Brief Pain Inventory, the Short Form 36 Health Survey, and the Owestry Disability Index. Time periods were consolidated into 3: postoperatively ≤1 week, 1 week to 1 year, and ≥1 year. Change in analgesic use was also studied. Data were compared by using nonparametric tests and matched t tests for temporally linked data.
resultsPatients achieved a decrease in pain across all consolidated time periods. Pain, as measured on a 10-point scale, decreased by 4.8 points up to 1 week, 4.6 points up to 1 year, and 4.4 points after a year (P < .001). Decrease in pain was apparent early after treatment and was sustained with time. Kyphoplasty and vertebroplasty were equally effective in reducing pain scores because differences between procedures for each time period were insignificant (P < .9 for <1 week, P < 1.0 for ≤1 year, and P < .9 for >1 year.
conclusionsOur analysis demonstrates that vertebral augmentation is effective in patients with multiple myeloma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.