Evidence map›Paper›PMID 23867888›Full record

Trial reportAmerican journal of physical medicine & rehabilitation2013

Contralaterally controlled neuromuscular electrical stimulation for recovery of ankle dorsiflexion: a pilot randomized controlled trial in patients with chronic post-stroke hemiplegia.

Jayme S Knutson, Kristine Hansen, Jennifer Nagy, Stephanie N Bailey, Douglas D Gunzler, Lynne R Sheffler, John Chae

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of physical medicine & rehabilitation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02199795 (Functional Electrical Stimulation Mediated Neuroplasticity), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02199795 nacompletednot on this mapstarted 2014, after this paper: background citation

Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in Stroke

TypeinterventionalSponsorMetroHealth Medical CenterRan2014 to 2015Enrolled7ConditionsStroke, Hemiparesis, FootdropArmsContralaterally Controlled Neuromuscular Electrical Stimulation, Cyclic Neuromuscular Electrical Stimulation
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Neuromuscular Electrical Stimulation for Motor Restoration in Hemiplegia.Physical medicine and rehabilitation clinics of North America · 2015
    Review
  9. Article
  10. The role of electrical stimulation therapy in ophthalmic diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Jayme S KnutsonDepartment of Physical Medicine and Rehabilitation, Case Western Reserve University, Cleveland, Ohio, USA.
Kristine Hansen
Jennifer Nagy
Stephanie N Bailey
Douglas D Gunzler
Lynne R Sheffler
John Chae
Deutsche Dystonie Gesellschaft · DEMetroHealth · USLouis Stokes Cleveland VA Medical Center · USMetroHealth Medical Center · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024989 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI DAVIS, PAMELA B · 2007 to 2011
$53.7M
Clinical and Translational Science Collaborative of ClevelandKL2TR000440 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$11.1M
Contralaterally Controlled NMES in Chronic Ankle Dorsiflexor Paresis after StrokeR21HD061593 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI KNUTSON, JAYME S. · 2009 to 2010
$422k
NCATS NIH HHS KL2 TR000440NCRR NIH HHS UL1 RR024989NCRR NIH HHS UL1RR024989NICHD NIH HHS R21 HD061593NICHD NIH HHS R21HD061593
6 · The paper itself

Abstract

objectiveThe aim of this study was to compare the effects of contralaterally controlled neuromuscular electrical stimulation (CCNMES) vs. cyclic neuromuscular electrical stimulation (NMES) on lower extremity impairment, functional ambulation, and gait characteristics.

designTwenty-six survivors of stroke with chronic (≥6 mos) foot drop during ambulation were randomly assigned to 6 wks of CCNMES or cyclic NMES. Both groups had ten sessions per week of self-administered home application of either CCNMES or cyclic NMES plus two sessions per week of gait training with a physical therapist. Primary outcomes included lower extremity Fugl-Meyer score, modified Emory Functional Ambulation Profile, and gait velocity. Assessments were made at pretreatment and posttreatment and at 1 and 3 mos after treatment.

resultsThere were no significant differences between the groups in the outcome trajectories for any of the measures. With data from both groups pooled, there were significant but modest and sustained improvements in the Fugl-Meyer score and the modified Emory Functional Ambulation Profile but not in gait velocity.

conclusionsThe results support the hypothesis that gait training combined with either CCNMES or cyclic NMES reduces lower extremity impairment and functional ambulation but do not support the hypothesis that CCNMES is more effective than cyclic NMES in patients with chronic post-stroke hemiplegia.

Indexed as

AdultAgedAnkleElectric Stimulation TherapyFemaleGaitHemiplegiaHumansMaleMiddle AgedMotor ActivityPilot ProjectsRange of Motion, ArticularRecovery of FunctionStrokeTreatment Outcome

Identifiers

PMID23867888
PMCPMC3786455
OpenAlexW2417903010

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.