Evidence map›Paper›PMID 23867611›Full record

ReviewInternational journal of molecular sciences2013

Could radiotherapy effectiveness be enhanced by electromagnetic field treatment?

Francisco Artacho-Cordón, María del Mar Salinas-Asensio, Irene Calvente, Sandra Ríos-Arrabal, Josefa León, Elisa Román-Marinetto, Nicolás Olea, María Isabel Núñez

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francisco Artacho-CordónDepartment of Radiology and Physical Medicine Av. Madrid s/n, Granada 18012, Spain. fartacho@live.com
María del Mar Salinas-Asensio
Irene Calvente
Sandra Ríos-Arrabal
Josefa León
Elisa Román-Marinetto
Nicolás Olea
María Isabel Núñez

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the main goals in radiobiology research is to enhance radiotherapy effectiveness without provoking any increase in toxicity. In this context, it has been proposed that electromagnetic fields (EMFs), known to be modulators of proliferation rate, enhancers of apoptosis and inductors of genotoxicity, might control tumor recruitment and, thus, provide therapeutic benefits. Scientific evidence shows that the effects of ionizing radiation on cellular compartments and functions are strengthened by EMF. Although little is known about the potential role of EMFs in radiotherapy (RT), the radiosensitizing effect of EMFs described in the literature could support their use to improve radiation effectiveness. Thus, we hypothesized that EMF exposure might enhance the ionizing radiation effect on tumor cells, improving the effects of RT. The aim of this paper is to review reports of the effects of EMFs in biological systems and their potential therapeutic benefits in radiotherapy.

Indexed as

Electromagnetic FieldsApoptosisCell MembraneCell NucleusHumansMAP Kinase Signaling SystemNeoplasmsRadiation, IonizingRadiation-Sensitizing AgentsRadiation-Sensitizing Agents

Identifiers

PMID23867611
PMCPMC3742283

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.