ArticleBlood transfusion = Trasfusione del sangue2013
Survey on the prevention and incidence of haemolytic disease of the newborn in Italy.
Article in Blood transfusion = Trasfusione del sangue, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Patient experience and burden of haemolytic disease of the foetus and newborn: a systematic review.BMC pregnancy and childbirth · 2025Pooled it
- Hemolytic disease of the fetus and newborn: systematic literature review of the antenatal landscape.BMC pregnancy and childbirth · 2023Pooled it
- Recommendations for the prevention and treatment of haemolytic disease of the foetus and newborn.Blood transfusion = Trasfusione del sangue · 2015Guideline
- Double-filtration plasmapheresis as an adjunct to therapy for severe early-onset maternal erythrocyte alloimmunization.BMC pregnancy and childbirth · 2025Article
- Hemolytic disease of the fetus and newborn: rapid review of postnatal care and outcomes.BMC pregnancy and childbirth · 2023Review
- Live birth prevalence of hemolytic disease of the fetus and newborn in the United States from 1996 to 2010.AJOG global reports · 2023Article
- Case report: Double filtration plasmapheresis (DFPP) for severe rhesus-D alloimmunization in two pregnant patients.Frontiers in pediatrics · 2023Article
- Article
- Severe haemolytic disease of a newborn with variant D mimicking blocked-D phenomenon.BMJ case reports · 2019Article
- Frequency of Red Cell Alloantibodies in Pregnant Females of Navsari District: An Experience that Favours Inclusion of Screening for Irregular Erythrocyte Antibody in Routine Antenatal Testing Profile.Journal of obstetrics and gynaecology of India · 2018Article
- Recommendations for transfusion therapy in neonatology.Blood transfusion = Trasfusione del sangue · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn 2010, the Italian Society of Immunohaematology and Transfusion Medicine (SIMTI) carried out a survey of the incidence of haemolytic disease of the newborn (HDN) and the prevention of HDN caused by anti-Rh(D) in Italian Transfusion Structures (TS). MATERIALS AND
methodsA questionnaire divided into the following five sections was administered: (i) types of services provided and maintenance of legally required registers, (ii) immunoprophylaxis (IP), (iii) red cell typing and searches for irregular antibodies, (iv) evaluation of foetal-maternal haemorrhage (FMH), and (v) incidence of HDN in 2010. Of the 280 TS sent the questionnaire, 176 (63%) replied.
resultsA HDN register was available in 55.5% of the TS (n =91). Immunoprophylaxis with a dose of anti-D IgG was given to all Rh(D) negative and Rh(D) variant puerpera with Rh(D) positive newborns: in more than 93% of cases the dose was between 1,500 IU (300 μg) and 1,250 IU (250 μg). Antenatal IP between the 25(th) and 28(th) week was proposed by 42 TS (26%). Seventy percent of the TS (n =115) did not make any evaluation of FMH. The number of births surveyed in 2010 was 203,384, the number of Rh(D) negative pregnancies was 13,569, while anti-D antibodies were present in 245 pregnancies. There were 111 cases of HDN due to anti Rh(D) incompatibility and in 40 of these, intrauterine transfusion (n =8) or exchange transfusion (n =32) was necessary. In 94 cases HDN was due to other irregular antibodies: in 4 of these cases intrauterine transfusion was needed and in 11 other recourse was made of exchange transfusion. Finally, there were 1,456 newborns with ABO HDN of whom 13 underwent exchange transfusion. DISCUSSION: The data collected give a picture of the incidence of HDN in Italy and of the methods of managing IP and could form the basis for an update of the SIMTI recommendations on the management and prevention of this disease.
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