Community-onset Staphylococcus aureus infections presenting to general practices in South-eastern Australia.

C M Bennett, G W Coombs, G M Wood, B P Howden, L E A Johnson, D White, P D R Johnson

Open access · bronzeAbstract read

In one paragraph

Article in Epidemiology and infection, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it

0cells of the map it votes in

7citing papers in PubMed

1.2field-weighted citation impact, top 22% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

Virulence factors and clonal diversity of Staphylococcus aureus in colonization and wound infection with emphasis on diabetic foot infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
Review
Incidence of community onset MRSA in Australia: least reported where it is Most prevalent.Antimicrobial resistance and infection control · 2019
Article
High burden of complicated skin and soft tissue infections in the Indigenous population of Central Australia due to dominant Panton Valentine leucocidin clones ST93-MRSA and CC121-MSSA.BMC infectious diseases · 2017
Observational
Bacterial skin and soft tissue infections.Australian prescriber · 2016
Review
A Prescription for Resistance: Management of Staphylococcal Skin Abscesses by General Practitioners in Australia.Frontiers in microbiology · 2016
Article
Community-associated methicillin-resistant Staphylococcus aureus transmission in households of infected cases: a pooled analysis of primary data from three studies across international settings.Epidemiology and infection · 2015
Article
Prostatic abscesses and severe sepsis due to methicillin-susceptible Staphylococcus aureus producing Panton-Valentine leukocidin.BMC infectious diseases · 2014
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

C M BennettThe University of Melbourne, Melbourne, Australia.

G W CoombsDepartment of Microbiology and Infectious Diseases, PathWest Laboratory Medicine-WA, Royal Perth Hospital, Australia.

G M WoodAustin Health, Melbourne, Australia.

B P HowdenThe University of Melbourne, Melbourne, Australia.

L E A JohnsonThe University of Melbourne, Melbourne, Australia.

D WhiteThe University of Melbourne, Melbourne, Australia.

P D R JohnsonThe University of Melbourne, Melbourne, Australia.

University of Melbourne · AUAustin Health · AUCurtin University · AUDeakin University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Community-acquired Staphylococcus aureus infections are a public health concern, yet little is known about infections that do not present to hospital. We identified community-onset S. aureus infections via specimens submitted to a community-based pathology service. Referring doctors confirmed eligibility and described infection site, severity and treatment. Isolates were characterized on antibiotic resistance, PFGE, MLST/SCCmec, and Panton-Valentine leukocidin (PVL), representing 106 community-onset infections; 34 non-multiresistant methicillin-resistant S. aureus (nmMRSA) (resistant to <3 non-β-lactam antibiotics), 15 multiply antibiotic-resistant MRSA (mMRSA) and 57 methicillin-sensitive S. aureus (MSSA). Most (93%) were skin and soft tissue infections. PVL genes were carried by 42% of nmMRSA isolates [95% confidence interval (CI) 26-61] and 15% of MSSA (95% CI 8-28). PVL was associated with infections of the trunk, head or neck (56·4% vs. 24·3%, P=0·005) in younger patients (23 vs. 52 years, P<0·001), and with boils or abscesses (OR 8·67, 95% CI 2·9-26·2), suggesting underlying differences in exposure and/or pathogenesis.

Indexed as

AdultAnti-Bacterial AgentsCommunity-Acquired InfectionsDrug Resistance, BacterialHumansMethicillin-Resistant Staphylococcus aureusMiddle AgedPolymerase Chain ReactionPrevalenceSeverity of Illness IndexStaphylococcal InfectionsStaphylococcus aureusVictoriaVirulenceAnti-Bacterial Agents

Identifiers

PMID23866772

DOI10.1017/S0950268813001581

PMCPMC9151107

OpenAlexW2012845179

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.