ArticleThe New phytologist2013
Allelic variation in two distinct Pseudomonas syringae flagellin epitopes modulates the strength of plant immune responses but not bacterial motility.
Article in The New phytologist, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed.
- Beyond the Halo: Molecular Mechanisms and Ecological Aspects of the Infection Strategy ofInternational journal of molecular sciences · 2026Review
- Current Understanding of Cell-Surface Immune Receptors for MAMPs and Plant Parasites in the Solanaceae Family.Molecular plant pathology · 2026Review
- Deciphering the genomic and functional basis of virulence and immune modulation inFrontiers in microbiology · 2026Article
- Heterologous expression of Arabidopsis FLS2 in Nicotiana benthamiana confers responsiveness to Ralstonia flg22 and activation of anti-bacterial immunity.Plant biotechnology journal · 2025Article
- The resistance awakens: Diversity at the DNA, RNA, and protein levels informs engineering of plant immune receptors from Arabidopsis to crops.The Plant cell · 2025Review
- Engineering and application of multiepitope recombinant proteins to enhance resistance toFrontiers in plant science · 2025Article
- Arabidopsis SBT5.2 and SBT1.7 subtilases mediate C-terminal cleavage of flg22 epitope from bacterial flagellin.Nature communications · 2024Article
- Natural variation in the pattern-triggered immunity response in plants: Investigations, implications and applications.Molecular plant pathology · 2024Review
- Tomato receptor-like cytoplasmic kinase Fir1 is involved in flagellin signaling and preinvasion immunity.Plant physiology · 2023Article
- Suppression of citrus canker disease mediated by flagellin perception.Molecular plant pathology · 2023Article
- Prevention of Stomatal Entry as a Strategy for Plant Disease Control against Foliar PathogenicPlants (Basel, Switzerland) · 2023Review
- Allelic variation in the indoleacetic acid-lysine synthase gene of the bacterial pathogenFrontiers in plant science · 2023Article
- Two NewMicrobiology spectrum · 2022Article
- Loss of function of the bHLH transcription factor Nrd1 in tomato enhances resistance to Pseudomonas syringae.Plant physiology · 2022Article
- Plant immunity: Rice XA21-mediated resistance to bacterial infection.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Time-series transcriptome ofFrontiers in plant science · 2022Article
- Plants as a realized niche for Listeria monocytogenes.MicrobiologyOpen · 2021Review
- Altered metabolomic states elicited by Flg22 and FlgII-28 in Solanum lycopersicum: intracellular perturbations and metabolite defenses.BMC plant biology · 2021Article
- Molecular Characterization of Differences between the Tomato Immune Receptors Flagellin Sensing 3 and Flagellin Sensing 2.Plant physiology · 2020Article
- An immune receptor complex evolved in soybean to perceive a polymorphic bacterial flagellin.Nature communications · 2020Article
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Authors and funding
10 authors.
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Abstract
The bacterial flagellin (FliC) epitopes flg22 and flgII-28 are microbe-associated molecular patterns (MAMPs). Although flg22 is recognized by many plant species via the pattern recognition receptor FLS2, neither the flgII-28 receptor nor the extent of flgII-28 recognition by different plant families is known. Here, we tested the significance of flgII-28 as a MAMP and the importance of allelic diversity in flg22 and flgII-28 in plant-pathogen interactions using purified peptides and a Pseudomonas syringae ∆fliC mutant complemented with different fliC alleles. The plant genotype and allelic diversity in flg22 and flgII-28 were found to significantly affect the plant immune response, but not bacterial motility. The recognition of flgII-28 is restricted to a number of solanaceous species. Although the flgII-28 peptide does not trigger any immune response in Arabidopsis, mutations in both flg22 and flgII-28 have FLS2-dependent effects on virulence. However, the expression of a tomato allele of FLS2 does not confer to Nicotiana benthamiana the ability to detect flgII-28, and tomato plants silenced for FLS2 are not altered in flgII-28 recognition. Therefore, MAMP diversification is an effective pathogen virulence strategy, and flgII-28 appears to be perceived by an as yet unidentified receptor in the Solanaceae, although it has an FLS2-dependent virulence effect in Arabidopsis.
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